Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/27784
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 18074/20272 (89%)
造访人次 : 4308745      在线人数 : 5644
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/27784


    標題: Biochemical and molecular analyses to determine pyrethroid resistance in Aedes aegypti
    作者: Lin, Ying-Hsi
    Tsen, Wei-Lun
    Tien, Nai-Yueh
    Luo, Yi-Pey
    貢獻者: 生物科技系
    關鍵字: Aedes Aegypti
    Permethrin Resistance
    Knockdown Resistant.
    Standard Glass Cylinder Method
    Detoxification Enzyme Activity
    Taqman (R) Probe Assay
    日期: 2013-10
    上傳時間: 2014-05-26 10:43:32 (UTC+8)
    出版者: Academic Press Inc Elsevier Science
    摘要: Dengue fever is an important mosquito-borne viral disease in Taiwan. Insecticide resistance has been shown to significantly reduce the efficacy of vector control interventions. The detection of insecticide resistance is an important component in mosquito abatement programs. In this study, we used the insecticide-impregnated papers bioassay method to reveal high levels of resistance to permethrin in the LYPR and field strains of Aedes aegypti. We used the standard glass cylinder method to observe the knockdown effect of paralysis within 2 to 4 minutes after exposing mosquitoes to pyrethroid vapors. Biochemical assays showed elevated detoxification enzyme activities. Glutathione S-transferases, monooxygenases and beta-esterases were the enzymes predominantly responsible for the permethrin resistance of Ae. aegypti in Taiwan. Molecular screening for common insecticide target-site mutations revealed the presence of V1023G and D1794Y mutations. Pearson's correlation analysis was used to investigate the correlations between the allelic frequency of kdr mutation associated increase with the LC50 values of permethrin and the KT50 values of pyrethroid vaporizers. These findings will be used to assess resistance levels, estimate resistance potential, and formulate monitoring and resistance management strategies. (C) 2013 Elsevier Inc. All rights reserved.
    關聯: Pesticide Biochemistry And Physiology v.107 n.2 pp.266-276
    显示于类别:[生物科技系(所)] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    index.html0KbHTML1846检视/开启


    在CNU IR中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈