Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/27651
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 18074/20272 (89%)
造訪人次 : 4106079      線上人數 : 5861
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋


    請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/27651


    標題: Antioxidant and anti-inflammatory properties of Dichondra repens Forst. and its reference compounds
    作者: Sheu, Ming-Jyh
    Deng, Jeng-Shyan
    Huang, Ming-Hsing
    Liao, Jung-Chun
    Wu, Chieh-Hsi
    Huang, Shyh-Shyun
    Huang, Guan-Jhong
    Sheu, Ming-Jyh�
    貢獻者: 化妝品應用與管理系
    關鍵字: Dichondra Repens
    Antioxidant
    Anti-Inflammation
    No
    Tnf-Alpha
    Mda
    日期: 2012-05-15
    上傳時間: 2014-03-21 16:16:30 (UTC+8)
    出版者: Elsevier Sci Ltd
    摘要: Dichondra repens (DR) is the main constituent in herbal beverages and consumed daily as a nutrition supplement for the liver in Taiwan. This study investigated the antioxidant and anti-inflammatory effects of D. repens ethanol extract (EDR) and its reference compounds ex vivo and in vivo. Fingerprint chromatograms (from HPLC) indicated that EDR contained vanillin, umbelliferone and scopoletin. EDR was evaluated for its antioxidant effects and LPS-induced NO production in RAW 264.7 cells. EDR decreased the LPS-induced NO production and expressions of iNOS and COX-2 in RAW 264.7 cells. In vivo anti-inflammatory activities of EDR were assessed in mouse paw oedema, induced by X-carrageenan (Carr). We investigate the antioxidant mechanism of EDR via studies of the activities of catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx) in the liver and the levels of malondialdehyde (MDA) and nitrite oxide (NO) in the oedematous paw. Serum NO and TNF-alpha were also measured. EDR exerts anti-inflammatory effects by suppressing TNF-alpha NO, and might be related to the decrement of the level of MDA in the oedema paw via increasing the activities of CAT, SOD and GPx in the liver. The results show that EDR might be a natural antioxidant and anti-inflammatory agent. (C) 2011 Elsevier Ltd. All rights reserved.
    關聯: Food Chemistry, 132(2), 1010-1018
    顯示於類別:[化妝品應用與管理系(所)] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    index.html0KbHTML2207檢視/開啟


    在CNU IR中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋