Novel phenolic glucoside, origanoside, protects against oxidative damage and modulates antioxidant enzyme activity

doi:10.1016/j.foodres.2011.03.041

Chia Nan University of Pharmacy & Science Institutional Repository > 藥理學院 > 化妝品應用與管理系(所) > 期刊論文 > Item 310902800/26669

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/26669

標題:	Novel phenolic glucoside, origanoside, protects against oxidative damage and modulates antioxidant enzyme activity
作者:	Chou, Tzung-Han Ding, Hsiou-Yu Chan, Leong-Perng Liang, Jing-Yao Liang, Chia-Hua
貢獻者:	化粧品科技研究所化粧品應用與管理系
關鍵字:	Antioxidant Origanoside Origanum vulgare Oxidative stress
日期:	2011-06
上傳時間:	2013-06-03 15:52:51 (UTC+8)
出版者:	Elsevier
摘要:	Our previous research demonstrated that a novel phenolic glucoside, origanoside, isolated from Origanum vulgare, exhibits significant antimelanogenesis activity. The present study was designed to investigate whether origanoside may serve as a quencher of oxidative insults and is involved in antimelanogenesis. It is found that origanoside exhibit the radical-scavenging capacity of 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS+) and superoxide anion radical (O2−), the reducing power, and the inhibition ability of lipid peroxidation (LP). Pretreatment with origanoside in hydrogen peroxide (H2O2)-treated BNLCL2 and HaCaT cells increased the activities of catalase (CAT) and glutathione peroxidase (GPx), potentially reducing the amount of reactive oxygen species (ROS) generation. These findings confirm the cytoprotective effect of origanoside in hepatocytes and keratinocytes, suggesting that origanoside exhibits antioxidant activities and may be a useful food additive.
關聯:	Food Research International 44(5), pp. 1496-1503
显示于类别:	[化妝品應用與管理系(所)] 期刊論文

文件中的档案:

档案	描述	大小	格式	浏览次数
index.html		0Kb	HTML	2296	检视/开启

在CNU IR中所有的数据项都受到原著作权保护.

TAIR相关文章

数据加载中.....