New Dimeric Analogs of 2-Aminodipyrido[L,2-A:3 ,2,-D] Imidazole : Synthesis And Interaction With DNA

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標題:	New Dimeric Analogs of 2-Aminodipyrido[L,2-A:3 ,2,-D] Imidazole : Synthesis And Interaction With DNA
作者:	Ching-Shing Lee Yuichi Hashimoto Toshiharu Ohta Koichi Shudo Toshihiko Okamoto
關鍵字:	intercalation 2-aminodipyrido〔1,2-a:3,2-d〕imidazole DNA melting temperature of DNA dimeric intercalator
日期:	1983
上傳時間:	2012-11-16 09:01:27 (UTC+8)
摘要:	New dimeric analogs of intercalative 2-aminodipyrido - [1,2-a:3 ,2-d]imidazole (Glu-P-2), a potent muta-carcinogen isolated from a pyrolysate of L-glutamic acid, were synthesized. The high affinity of these compounds to DNA was demonstrated by fluorescence spectroscopic studies and by their effects in raising the melting temperature (TM) of DNA.
關聯:	嘉南學報 9, A37-A40 轉載自 Chem. Pharm. Bull. ,30(8),3046-3049
显示于类别:	[嘉南學報] 9 期 (1983)

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