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https://ir.cnu.edu.tw/handle/310902800/25955
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| 標題: | New Dimeric Analogs of 2-Aminodipyrido[L,2-A:3 ,2,-D] Imidazole : Synthesis And Interaction With DNA |
| 作者: | Ching-Shing Lee
Yuichi Hashimoto
Toshiharu Ohta
Koichi Shudo
Toshihiko Okamoto |
| 關鍵字: | intercalation
2-aminodipyrido〔1,2-a:3,2-d〕imidazole
DNA
melting temperature of DNA
dimeric intercalator |
| 日期: | 1983 |
| 上傳時間: | 2012-11-16 09:01:27 (UTC+8) |
| 摘要: | New dimeric analogs of intercalative 2-aminodipyrido - [1,2-a:3 ,2-d]imidazole (Glu-P-2), a potent muta-carcinogen isolated from a pyrolysate of L-glutamic acid, were synthesized. The high affinity of these compounds to DNA was demonstrated by fluorescence spectroscopic studies and by their effects in raising the melting temperature (TM) of DNA. |
| 關聯: | 嘉南學報 9, A37-A40
轉載自 Chem. Pharm. Bull. ,30(8),3046-3049 |
| 显示于类别: | [嘉南學報] 9 期 (1983)
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