New Dimeric Analogs of 2-Aminodipyrido[L,2-A:3 ,2,-D] Imidazole : Synthesis And Interaction With DNA

CNU IR > Chna Nan Annual Bulletin > Vol.9 (1983) > Item 310902800/25955

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题名:	New Dimeric Analogs of 2-Aminodipyrido[L,2-A:3 ,2,-D] Imidazole : Synthesis And Interaction With DNA
作者:	Ching-Shing Lee Yuichi Hashimoto Toshiharu Ohta Koichi Shudo Toshihiko Okamoto
关键词:	intercalation 2-aminodipyrido〔1,2-a:3,2-d〕imidazole DNA melting temperature of DNA dimeric intercalator
日期:	1983
上传时间:	2012-11-16 09:01:27 (UTC+8)
摘要:	New dimeric analogs of intercalative 2-aminodipyrido - [1,2-a:3 ,2-d]imidazole (Glu-P-2), a potent muta-carcinogen isolated from a pyrolysate of L-glutamic acid, were synthesized. The high affinity of these compounds to DNA was demonstrated by fluorescence spectroscopic studies and by their effects in raising the melting temperature (TM) of DNA.
關聯:	嘉南學報 9, A37-A40 轉載自 Chem. Pharm. Bull. ,30(8),3046-3049
显示于类别:	[Chna Nan Annual Bulletin] Vol.9 (1983)

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