Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/25388
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 17778/20119 (88%)
造訪人次 : 12260932      線上人數 : 109
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    請使用永久網址來引用或連結此文件: http://ir.cnu.edu.tw/handle/310902800/25388


    標題: Simultaneous analysis of nine components in patch preparations of Ru-Yi-Jin-Huang San by high-performance liquid chromatography
    作者: Horng-Liang Lay
    Chia-Chi Chen
    Shiow-Chyn Huang
    Thau-Ming Cham
    Tian-Shung Wu
    I-Hsin Lin
    貢獻者: 藥物科技研究所
    關鍵字: Ru-Yi-Jin-Huang-San
    Berberine
    Curcumin
    Imperatorin
    Magnolol
    Hesperidin
    Glycyrrhizin
    Emodin - Sennoside A - Sennoside B
    日期: 2010-04
    上傳時間: 2012-06-04 16:40:15 (UTC+8)
    摘要: A facile high-performance liquid chromatography (HPLC) method for the resolution and quantitative measurement of nine marker substances, the active ingredients in patch preparations of Ru-Yi-Jin-Huang-San, was established using gradient elution in the reversed-phase mode. These marker substances included berberine (Phellodendri Cortex), curcumin (Curcumae Rhizoma), imperatorin (Angelicae Dahuricae Radix), magnolol (Magnoliae Cortex), hesperidin (Citri Leiocarpae Exocarpium), glycyrrhizin (Glycyrrhizae Radix), and emodin, sennoside A, sennoside B (Rhei Rhizoma). The ingredients in the water-based and oil-based patches of the formula from different manufactures were also analyzed for quality evaluation. Extracted samples were analyzed by HPLC using a reversed-phase column (Inertsil 5 ODS-2, 4.6-mm I.D. ×250 mm) at 30°C and eluted with a mixture of 20 and 70% acetonitrile aqueous solution in gradient manner at a flow rate of 1.0 ml/min. The detection wavelength varied with time as follows: 275 nm, 0–72 min; 250 nm, 72–105 min; 220 nm, 105–145 min. Relative coefficients of variations of intra- and interday analysis were less than 5%. All the recoveries were 93.30–113.63%. This method could be applied for the simultaneous determination of nine marker substances in Ru-Yi-Jin-Huang-San.
    關聯: Journal of Natural Medicine 64(2):p.194-202
    顯示於類別:[藥學系(所)] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    99_160_j.pdf402KbAdobe PDF449檢視/開啟
    index.html0KbHTML874檢視/開啟


    在CNU IR中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋