Inhibitory effects of resveratrol on the Epstein-Barr virus lytic cycle

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Title:	Inhibitory effects of resveratrol on the Epstein-Barr virus lytic cycle
Authors:	Ching-Yi Yiu Shih-Ying Chen Li-Kwan Chang Ya-Fang Chiu Tsuey-Pin Lin
Contributors:	保健營養系
Keywords:	resveratrol antiviral activity EBV
Date:	2010-10
Issue Date:	2012-05-21 16:30:02 (UTC+8)
Abstract:	Reactivation of Epstein-Barr virus (EBV) from latency to the lytic cycle is required for the production of viral particles. Here, we examine the capacity of resveratrol to inhibit the EBV lytic cycle. Our results show that resveratrol inhibits the transcription of EBV immediate early genes, the expression of EBV lytic proteins, including Rta, Zta, and EA-D and reduces viron production, suggesting that this compound may be useful for preventing the proliferation of the virus.
Relation:	Molecules 15(10)：p.7115-7124
Appears in Collections:	[Dept. of Health and Nutrition (including master's program)] Periodical Articles

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