Comparison of Dissolution-Enhancing Efficiency of Super Disintegrant When Used Alone or In Mixture

Chia Nan University of Pharmacy & Science Institutional Repository > 嘉南學報 > 22期 (1996) > Item 310902800/23013

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標題:	Comparison of Dissolution-Enhancing Efficiency of Super Disintegrant When Used Alone or In Mixture 超級崩散劑混合使用對溶離速率之影響
作者:	Shu-Yang Yen Chun-Ren Chen Ju-I Kao Ming-Huei Sun
貢獻者:	藥學系
關鍵字:	super disintegrant dissolution pH 超級崩散劑溶離酸鹼度
日期:	1996
上傳時間:	2010-09-17 14:27:41 (UTC+8)
摘要:	Tradidonally super disintegrant is used alone in a tablet to enhance the dissolution of active ingredient. In this study the effect of using mixture of super disintegrants was investigated. It was found that the mixture of Primojel and Kollidon CL shows a synergistic effect in terms of disso-lution-enhancing ehiciency. However, this effect is also dependent on dUueot and pH of the environment. 傳統上超級崩散劑都單獨使用來促進主成分之溶離速率。本研究探討混合使用時會使彼此效果增強，而優於單獨使用。但這種作用又受酸鹼度及賦形劑之影響。
關聯:	嘉南學報 22期：p.171-177
顯示於類別:	[嘉南學報] 22期 (1996) [藥學系(所)] 期刊論文

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