Local scaling and multifractal spectrum analyses of DNA sequences – GenBank data analysis

doi:10.1016/j.chaos.2007.09.078

CNU IR > College of Smart Living > Dept. of Information Management > Periodical Articles > Item 310902800/22602

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/22602

Title:	Local scaling and multifractal spectrum analyses of DNA sequences – GenBank data analysis
Authors:	Zhi-Yuan Su Tzuyin Wu Shu-Yin Wang
Contributors:	資訊管理系
Date:	2009-05
Issue Date:	2010-04-13 14:09:55 (UTC+8)
Abstract:	Base sequences of deoxyribonucleic acid (DNA) in an organism carry all the instructions regarding its growth and development. On the surface, such sequences seem irregular; yet in reality, they are symbolic sequences with an organized structure. This study investigates the characteristics of base arrangement and distribution in DNA sequences from the fractal theory viewpoint. In addition to multifractal features demonstrated by the DNA sequence, this study also compares the multifractal spectra derived from a particular family of gene among several different species. The results reveal that a considerable correlation exists between base distribution and evolutionary order. Furthermore, local scaling exponent (Ho¨ lder exponent) differences between coding segments (exon) and noncoding segments (intron) are also examined. It is suggested that such differences in the local distribution of bases can be applied to find coding segments within the DNA sequence that is to be translated into protein. This local scaling analysis is feasible and has the potential to become an effective tool for rapid location of possible coding sites in DNA sequences. The authors hope that future studies using more complicated bioinformatics methods for analyzing DNA sequences can benefit from this study.
Relation:	Chaos, Solitons and Fractals 40:p.1750-1765
Appears in Collections:	[Dept. of Information Management] Periodical Articles

Files in This Item:

File	Description	Size	Format
Local scaling and multifractal spectrum analyses of DNA sequences – GenBank data analysis .pdf	Local scaling and multifractal spectrum analyses of DNA sequences – GenBank data analysis	929Kb	Adobe PDF	1654	View/Open

Loading...