研究主要目的是考慮寵物犬毛髮與皮膚之「等電點生理學」進行寵物犬洗毛精技術之開發。其方法分四階段來進行：(1)市售寵物犬專用洗毛精pH值之測定，(2)進行寵物犬皮膚的pH值之測定，(3)寵物犬洗毛精新配方之開發研究，(4)寵物犬洗毛精安全性之測定。結果發現，市售寵物犬專用洗毛精酸鹼值之比較pH值之範圍由6.01-8.06皆有；寵物犬皮膚的pH值在6.00-6.50之間，屬於微酸性；洗毛精之新配方對寵物犬皮膚的刺激性評估呈陰性反應，飼主可放心使用。 This study was to explore a new shampoo for pet dog according to the isoelectric physiology of pet dog hair and skin. There were four stages for completing this work: (1) measuring the pH of some commercial dog shampoos, (2) detecting pH on the dog skin, (3) developing some new formulas of dog shampoo and (4) investigating the safety of new dog shampoo. Results show that the pHs of the commercial dog shampoos are between 6.01-8.06. However, the pH on the dog skin is in the range of 6.00-6.50. The new dog shampoo developed in this study has a similar pH range with dog skin. In addition, the evaluation of the new shampoo for the irradiation on dog skin is negative. Therefore, this new shampoo can be applied for commercial purpose.