夏枯草的抗氧化和抗發炎活性探討

CNU IR > Pharmacy and Science > Dept. of Biotechnology (including master's program) > Chna Project > Item 310902800/194

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Title:	夏枯草的抗氧化和抗發炎活性探討 Studies on antioxidant capacity of Prunella vulgaris
Authors:	郭玫君
Contributors:	生物科技系
Keywords:	Prunella vulgaris 夏枯草 DPPH TEAC 氫氧自由基 Trolox equivalent antioxidant capacity (TEAC) hydroxyl radical
Date:	2007
Issue Date:	2008-05-13 14:28:58 (UTC+8)
Publisher:	台南縣：嘉南藥理科技大學生物科技系
Abstract:	夏枯草台灣民間用來治療外傷的中草藥，其具有抗菌、抗病毒、及增強免疫力等作用，因此其極具開發之潛能。本研究結果顯示夏枯草的乙醇萃取物可以清除1,1-diphenyl-2-picrylhydrazyl (DPPH) 和氫氧自由基，其IC50 分別為 76.45 ± 1.54g/mL和 0.75mg/mL。在TEAC分析方面，夏枯草的乙醇萃取物清除ABTS能力與標準品trolox相較之下並不佳。總括來看，夏枯草萃出物具有抗氧化能力，值得進ㄧ步研究和確認其指標成分。 Prunella vulgaris is a native traditional anti-bacterial herb for internal and external wounds healing in Taiwan. Results in this study show that the ethanol extract of Prunella vulgaris exhibited a strong ability to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) and hydroxyl radicals, the IC50 values for DPPH and hydroxyl radicals scavenging of the ethanol crude extract are 76.45 ± 1.54g/mL and 0.75mg/mL, respecally. On the other hand, the ethanol only showed slightly eliminating activity of ABTS radical cation on TEAC analysis. In summary, these data indicated that Prunella vulgaris is a potential ROS scavenger.
Relation:	計畫編號 : CN9651
Appears in Collections:	[Dept. of Biotechnology (including master's program)] Chna Project

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