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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/9206


    標題: 中藥槐米與地骨皮在化妝品之生物活性研究
    Studies on the cosmetic bioactivity for Sophora japonica L. and Lycium chinense Mill.
    作者: 馮皓雲
    Hao-yun Feng
    貢獻者: 丁秀玉
    嘉南藥理科技大學:化妝品科技研究所
    關鍵字: 槐米
    美白
    抗氧化
    地骨皮
    antioxidative
    Lycium chinense Mill
    日期: 2007
    上傳時間: 2008-12-03 11:16:27 (UTC+8)
    摘要: 隨著經濟發展,時代進步,化妝品的需求量日益殷切。而在崇尚
    自然產品的趨勢下,目前的化粧品多是傾向運用天然植物做為原料或
    添加劑。故本研究選定以槐米及地骨皮二種中藥進行抗氧化及美白之
    分離純化。本研究從槐米的95%乙醇萃取物中分離純化而得四種純物
    質:Luteolin 7-O-β-D-glucoside (1)、Kaempferol (2)、Rutin (3)、
    Quercetin(4)。而由地骨皮的95%乙醇萃取物中分離純化而得一種純物
    質:Scopoletin (5)。由上述二種中藥分離的五個化合物,均具有掃除
    自由基DPPH 和抑制酪氨酸酶的活性。進一步對具有抑制酪氨酸酶活
    性的有效成分Kaempferol (2)進行酵素動力學的研究,發現其在抑制
    酪氨酸酶活性機制上是屬於競爭性的抑
    Following the development of economics, the cosmetics market
    has been boosted as well. The application of herb natural products as
    components of the cosmetic products is a trend at present in the cosmetic
    industry. Two herbs, Sophora japonica L. and Lycium chinense Mill.,
    were studied in order to isolate their antioxidative and whitening
    components. From the 95% ethanol extract of Sophora japonica L., four
    components were isolated: luteolin 7-O-β-D-glucoside (1), kaempferol
    (2), rutin (3) and quercetin (4). From the 95% ethanol extract of Lycium
    chinense Mill., one compound was isolated: scopoletin (5). Among of
    isolated five compounds, Luteolin 7-O-β-D-glucoside (1), kaempferol (2),
    rutin (3), quercetin (4), and scopoletin (5) show DPPH scavenging
    activity and inhibit tyrosinase activity. In the kinetic analysis, component
    kaempferol (2) was shown to inhibit mushroom tyrosinase in competitive
    manner.
    關聯: 校內校外均不公開
    Appears in Collections:[化妝品應用與管理系(所)] 博碩士論文

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