Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/883
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    標題: 茄紅素之固體製劑研發:錠劑劑型
    Investigation of solid products for lycopene:tablet dosage forms
    作者: 林恆弘
    貢獻者: 藥學系
    關鍵字: 茄紅素
    吸濕性
    固體製劑
    粉體
    錠劑
    崩散
    Lycopene
    Hygroscopicity
    solid product
    powder
    tablet
    disintegration
    日期: 2004
    上傳時間: 2008-06-06 16:24:42 (UTC+8)
    出版者: 台南縣:嘉南藥理科技大學藥學系
    摘要: 現今的消費者使用乾燥製品的情形相
    當普遍,就經濟上與方便性而言,其具有
    可增加製品的架貯期、減少包裝、降低價
    格與改善操作特性等優點。本研究中,乾
    燥之蕃茄粉末混合適當的賦形劑經壓製成
    為咀嚼錠或快速溶解之錠劑。接著評估其
    崩散劑性質—錠劑崩散時間與受壓破裂壓
    力;結果顯示,崩散劑的種類、添加模式、
    添加濃度與相對密度顯著影響錠劑的崩散
    時間,但對錠劑受壓破裂壓力的影響則不
    顯著。
    Dry products have a high level of
    popularity with today’s consumers.
    Dry mixes are economical and
    convenient with increased shelf-life,
    reduced packaging, decreased cost
    and improved handling properties. In
    the study, the dried tomato powder
    combined with the appropriated
    excipients was pressed into chewable
    or a quick dissolve tablet dosage
    form. The disintegrant properties –
    tablet disintegration time and
    crushing strength were evaluated.
    The results show that the kinds of
    disintegrants, the mode of addition
    of disintegrants, disintegrant
    concentration and relative density
    had a significant impact on the
    disintegration time, but not on the
    crushing strength.
    显示于类别:[藥學系(所)] 校內計畫

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