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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/31734


    標題: A new flavonol from the kino of Eucalyptus citriodora
    作者: Lee, Shwu-Woan
    Hung, Wei-Jing
    Chen, Zong-Tsi
    貢獻者: Chia Nan Univ Pharm & Sci, Dept Med Chem
    Chia Nan Univ Pharm & Sci, Dept Cosmet Sci
    Chia Nan Univ Pharm & Sci, Inst Cosmet Sci
    關鍵字: Eucalyptus citriodora
    kino
    lipoxygenase
    flavonoids
    日期: 2017
    上傳時間: 2018-11-30 15:54:41 (UTC+8)
    出版者: Taylor & Francis Ltd
    摘要: A new flavonol, 6-[1-(p-hydroxyphenyl)ethyl]rhamnocitrin (3) together with two known compounds, kaempferol (4) and 7-O-methyl aromadendrin (5) were isolated from the kino of Eucalyptus citriodora and their structures were elucidated on the basis of spectroscopic methods including 2D NMR spectra. Rhamnocitrin (1), 6-[1-(p-hydroxyphenyl)ethyl]-7-O-methyl aromadendrin (2), previously isolated from this plant and compounds 3-5 were tested for inhibitory activity against 15-lipoxygenase. All compounds exhibited moderate to strong inhibitory activities, of which compounds 2, 3 and 5 showed stronger inhibitory activity (IC50 19.7 +/- 0.5, 29.3 +/- 0.9 and 31.4 +/- 1.0M, respectively) than the positive control quercetin (IC50 37.5 +/- 0.8M).
    關聯: Natural Product Research, v.31, n.1, pp.37-42
    Appears in Collections:[化妝品應用與管理系(所)] 期刊論文
    [醫藥化學系 ] 期刊論文

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