A new flavonol from the kino of Eucalyptus citriodora

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Title:	A new flavonol from the kino of Eucalyptus citriodora
Authors:	Lee, Shwu-Woan Hung, Wei-Jing Chen, Zong-Tsi
Contributors:	Chia Nan Univ Pharm & Sci, Dept Med Chem Chia Nan Univ Pharm & Sci, Dept Cosmet Sci Chia Nan Univ Pharm & Sci, Inst Cosmet Sci
Keywords:	Eucalyptus citriodora kino lipoxygenase flavonoids
Date:	2017
Issue Date:	2018-11-30 15:54:41 (UTC+8)
Publisher:	Taylor & Francis Ltd
Abstract:	A new flavonol, 6-[1-(p-hydroxyphenyl)ethyl]rhamnocitrin (3) together with two known compounds, kaempferol (4) and 7-O-methyl aromadendrin (5) were isolated from the kino of Eucalyptus citriodora and their structures were elucidated on the basis of spectroscopic methods including 2D NMR spectra. Rhamnocitrin (1), 6-[1-(p-hydroxyphenyl)ethyl]-7-O-methyl aromadendrin (2), previously isolated from this plant and compounds 3-5 were tested for inhibitory activity against 15-lipoxygenase. All compounds exhibited moderate to strong inhibitory activities, of which compounds 2, 3 and 5 showed stronger inhibitory activity (IC50 19.7 +/- 0.5, 29.3 +/- 0.9 and 31.4 +/- 1.0M, respectively) than the positive control quercetin (IC50 37.5 +/- 0.8M).
Relation:	Natural Product Research, v.31, n.1, pp.37-42
Appears in Collections:	[Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles [Dept. of Food & Drug Industry and Inspective Technology] Periodical Articles

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