Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/31709
English  |  正體中文  |  简体中文  |  Items with full text/Total items : 16999/19305 (88%)
Visitors : 9774716      Online Users : 41
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item:

    Title: Constituents from the leaves of Clausena lansium and their anti-inflammatory activity
    Authors: Shen, De-Yang
    Kuo, Ping-Chung
    Huang, Shiow-Chyn
    Hwang, Tsong-Long
    Chan, Yu-Yi
    Shieh, Po-Chuen
    Ngan, Nguyen Thi
    Thang, Tran Dinh
    Wu, Tian-Shung
    Contributors: Natl Cheng Kung Univ, Coll Med, Sch Pharm,Natl Cheng Kung Univ Hosp
    Chia Nan Univ Pharm & Sci, Dept Pharm
    Chang Gung Univ, Coll Med, Grad Inst Nat Prod
    Chang Gung Univ Sci & Technol, Res Ctr Ind Human Ecol, Res Ctr Chinese Herbal Med
    Chang Gung Univ Sci & Technol, Coll Human Ecol, Grad Inst Hlth Ind Technol
    Chang Gung Mem Hosp, Dept Anesthesiol
    Southern Taiwan Univ Sci & Technol, Dept Biotechnol
    Tajen Univ, Dept Pharm
    Vinh Univ, Dept Chem
    Keywords: Clausenalansamide
    Electronic circular dichroism
    Single-crystal X-ray diffraction analysis
    Superoxide anion generation
    Date: 2017-01
    Issue Date: 2018-11-30 15:53:45 (UTC+8)
    Publisher: Springer Japan Kk
    Abstract: Five new acyclic amides, clausenalansamides C-G (1-5), clausenaline G (6) and (+/-)-5-(4-methylphenyl)-gamma-valerolactone (7) reported from the natural source for the first time, were characterized from the leaves of Clausena lansium. Their structures were established by spectroscopic and spectrometric methods, and the absolute configurations of new compounds 1-5 were determined by electronic circular dichroism and single-crystal X-ray diffraction analyses. Eighteen compounds were evaluated for their anti-inflammatory activity and only imperatorin (11) and wampetin (12) displayed significant inhibition of fMLP/CB-induced superoxide anion generation with IC50 values of 1.7 +/- 0.3 and 6.8 +/- 1.1 mu M, respectively.
    Appears in Collections:[Dept. of Pharmacy] Periodical Articles

    Files in This Item:

    File Description SizeFormat

    All items in CNU IR are protected by copyright, with all rights reserved.

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback