Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/31648
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 18057/20255 (89%)
造访人次 : 1514837      在线人数 : 846
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/31648


    標題: Hepatoprotective effects of raspberry (Rubus coreanus Miq.) seed oil and its major constituents
    作者: Teng, Hui
    Lin, Qiyang
    Li, Kang
    Yuan, Benyao
    Song, Hongbo
    Peng, Hongquan
    Yi, Lunzhao
    Wei, Ming-Chi
    Yang, Yu-Chiao
    Battino, Maurizio
    Cespedes Acuna, Carlos L.
    Chen, Lei
    Xiao, Jianbo
    貢獻者: Fujian Agr & Forestry Univ, Coll Food Sci
    Kiang Wu Hosp, Macau
    Kunming Univ Sci & Technol, Yunnan Food Safety Res Inst
    Chia Nan Univ Pharm & Sci, Dept Appl Geoinformat
    Kaohsiung Med Univ, Dept & Grad Inst Pharmacol
    Univ Europea Atlantico, Ctr Nutr & Hlth
    Univ Europea, Univ Nutr & Hlth, Dept Clin Sci
    Univ Bio Bio, Basic Sci Dept, Plant Biochem & Phytochem Ecol Lab
    Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med
    關鍵字: Raspberry seeds
    Fatty acids
    Extraction
    Antioxidant enzyme
    Hepatoprotection
    日期: 2017-12
    上傳時間: 2018-11-30 15:51:29 (UTC+8)
    出版者: Pergamon-Elsevier Science Ltd
    摘要: Raspberry seed is a massive byproduct of raspberry juice and wine but usually discarded. The present study employed a microwave-assisted method for extraction of raspberry seed oil (RSO). The results revealed that omega-6 fatty acids (linoleic acid and gamma-linolenic acid) were the major constituents in RSO. Cellular antioxidant enzyme activity such as superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) were investigated in HepG2 cells treated with RSO. Induction of the synthesis of several antioxidants in H2O2-exposed HepG2 cells was found. RSO increased the enzyme activity of SOD, CAT, and GPx in H2O2-exposed HepG2. Furthermore, RSO inhibited the phosphorylation of upstream mitogen-activated protein kinases (MAPK) such as c-Jun N-terminal kinase (c-JNK)and extracellular signal-regulated kinase (ERK). Taken together, the possible mechanisms to increase antioxidant enzyme activities in HepG2 may through the suppression of ERK and JNK phosphorylation. Raspberry seed oil exhibited good effects on the activities of the intracellular antioxidant enzymes and seems to protect the liver from oxidative stress through the inhibition of MAPKs. (C) 2017 Published by Elsevier Ltd.
    關聯: Food and Chemical Toxicology, v.110, pp.418-424
    显示于类别:[應用空間資訊系(所)] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    index.html0KbHTML1441检视/开启
    j.fct.2017.09.010.pdf1290KbAdobe PDF0检视/开启


    在CNU IR中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈