English  |  正體中文  |  简体中文  |  Items with full text/Total items : 16812/19099 (88%)
Visitors : 6035381      Online Users : 302
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/31642


    標題: Effect of enterovirus infections on asthma in young children: Anational cohort study
    作者: Yeh, Jun-Jun
    Lin, Cheng-Li
    Hsu, Wu-Huei
    貢獻者: Chia Yi Christian Hosp, Dept Family Med,Ditmanson Med Fdn
    Chia Nan Univ Pharm & Sci
    Meiho Univ
    China Med Univ Hosp, Management Off Hlth Data
    China Med Univ, Coll Med
    China Med Univ, Grad Inst Clin Med Sci, Coll Med
    China Med Univ, Sch Med, Coll Med
    China Med Univ Hosp, Div Pulm & Crit Care Med, Dept Internal Med
    關鍵字: asthma
    cohort study
    enterovirus
    日期: 2017-12
    上傳時間: 2018-11-30 15:51:16 (UTC+8)
    出版者: Wiley
    摘要: BackgroundWe conducted a cohort study to determine the relationship between enterovirus (EV) infection and asthma. Materials and methodsFrom the National Health Insurance Research Database of Taiwan, we identified patients who received a new diagnosis of asthma and concurrent treatment between January 2000 and December 2011 (EV cohort: n=208213; non-EV cohort: n=208213). Cox proportional hazards regression analysis was performed to determine and compare the adjusted hazard ratios (aHRs) of asthma between these 2 cohorts. Kaplan-Meier analysis was conducted to assess the differences in the cumulative incidence curves of asthma between the 2 cohorts. ResultsThe overall aHR of asthma was 1.48-fold higher in the EV cohort than in the non-EV cohort (95% confidence interval=1.45-1.50). The aHR of asthma was higher in the EV cohort than in the non-EV cohort, comprising children aged 5years, regardless of sex, sociodemographic factors (urbanization level and parental occupation) or comorbidities. The risk of asthma was higher in 1-3, 4-6, 7-9 and 10-12months (all P<.001), particularly in those with a higher frequency of admission (>5 per year). ConclusionThe incidence of asthma was higher in the EV cohort than in the non-EV cohort, comprising children aged 5years, regardless of sex, urbanization level, parental occupation or season. In particular, the risk of asthma was higher in children with a higher frequency of admission, even in the absence of atopy or other respiratory infections.
    關聯: European Journal of Clinical Investigation, v.47, n.12, 文獻號碼:UNSP e12844
    Appears in Collections:[嬰幼兒保育系] 期刊論文

    Files in This Item:

    File Description SizeFormat
    eci.12844.pdf168KbAdobe PDF19View/Open
    index.html0KbHTML58View/Open


    All items in CNU IR are protected by copyright, with all rights reserved.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback