English  |  正體中文  |  简体中文  |  Items with full text/Total items : 16812/19099 (88%)
Visitors : 6345293      Online Users : 209
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/28513


    標題: Asthma increases pulmonary thromboembolism risk: a nationwide population cohort study
    作者: Chung, Wei-Sheng
    Lin, Cheng-Li
    Ho, Feng-Ming
    Li, Ruei-Yuan
    Sung, Fung-Chang
    Kao, Chia-Hung
    Yeh, Jun-Jun
    貢獻者: 嬰幼兒保育系
    關鍵字: DEEP-VEIN THROMBOSIS
    ENDOTHELIAL DYSFUNCTION
    VENOUS THROMBOEMBOLISM
    ALLERGEN CHALLENGE
    EMBOLISM
    COAGULATION
    COPD
    PREVALENCE
    MORTALITY
    DISEASE
    日期: 2014-03
    上傳時間: 2015-05-06 21:19:00 (UTC+8)
    出版者: European Respiratory Soc Journals Ltd
    摘要: Studies on the association between asthma and pulmonary thromboembolism are considerably limited. We investigated whether pulmonary embolism is associated with asthma using a nationwide cohort study. We identified 31 356 patients with newly diagnosed asthma in 2002-2008 and 125 157 individuals without asthma randomly selected from the general population, frequency matched by age, sex and index year using the National Health Insurance Research Database. Both cohorts were followed-up until the end of 2010 to measure the incidence of pulmonary embolism. Cox proportional hazards regression analysis was used to measure the hazard ratio of pulmonary embolism for the asthmatic cohort, compared with the nonasthmatic cohort. We followed 186 182 person-years for asthmatic patients and 743 374 person-years for nonasthmatic subjects. The hazard ratio of pulmonary embolism was 3.24 for the asthmatic cohort, compared with the nonasthmatic cohort after adjusting for sex, age, comorbidities and oestrogen supplementation. The risk of developing pulmonary embolism significantly increased with the increased frequency of asthma exacerbation and hospitalisation. This nationwide cohort study suggests that the risk of developing pulmonary embolism is significantly increased in asthmatic patients compared to the general population. Frequent asthma exacerbation and hospitalisation are significantly associated with pulmonary embolism risk.
    關聯: European Respiratory Journal, v.43 n.3, pp.801-807
    Appears in Collections:[嬰幼兒保育系] 期刊論文

    Files in This Item:

    File Description SizeFormat
    28513.pdf304KbAdobe PDF755View/Open
    index.html0KbHTML476View/Open


    All items in CNU IR are protected by copyright, with all rights reserved.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback