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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/25955


    標題: New Dimeric Analogs of 2-Aminodipyrido[L,2-A:3 ,2,-D] Imidazole : Synthesis And Interaction With DNA
    作者: Ching-Shing Lee
    Yuichi Hashimoto
    Toshiharu Ohta
    Koichi Shudo
    Toshihiko Okamoto
    關鍵字: intercalation
    2-aminodipyrido〔1,2-a:3,2-d〕imidazole
    DNA
    melting temperature of DNA
    dimeric intercalator
    日期: 1983
    上傳時間: 2012-11-16 09:01:27 (UTC+8)
    摘要: New dimeric analogs of intercalative 2-aminodipyrido - [1,2-a:3 ,2-d]imidazole (Glu-P-2), a potent muta-carcinogen isolated from a pyrolysate of L-glutamic acid, were synthesized. The high affinity of these compounds to DNA was demonstrated by fluorescence spectroscopic studies and by their effects in raising the melting temperature (TM) of DNA.
    關聯: 嘉南學報 9, A37-A40
    轉載自 Chem. Pharm. Bull. ,30(8),3046-3049
    Appears in Collections:[嘉南學報] 9 期 (1983)

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