English  |  正體中文  |  简体中文  |  Items with full text/Total items : 16716/19011 (88%)
Visitors : 5843447      Online Users : 57
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/22185


    標題: Microwave-assisted acid hydrolysis of toluene diamine conjugates in urine samples for biomarkers in toluene diisocyanate analysis
    作者: Hui-Jung Yeh
    Wei-Chao Lin
    Shiann-Cherng Sheu
    Tung-Sheng Shih
    Lien-Huei Chen
    Ho-Yuan Chang
    貢獻者: 嬰幼兒保育系
    關鍵字: Toluene diisocyanate
    Toluene diamine
    Microwave-assisted heating
    Hydrolysis
    日期: 2007-06
    上傳時間: 2010-01-11 14:08:07 (UTC+8)
    摘要: Toluene diamines (TDAs) in urine have been used widely to determine the amount of toluene diisocyanate (TDI) absorbed by humans. Conventional hydrolysis to prepare a sample of urine takes approximately 16 h. An attempt is made to apply microwave-assisted heating (MAH) to reduce the duration of analysis. Urine collected from rats exposed to a mixture of 2,4- and 2,6-TDI was diluted with non-exposed human urine 1/1250-, 1/500- and 1/250-fold. The urine samples were hydrolyzed by both conventional heating and MAH. The hydrolysis efficiency obtained using MAH significantly exceeded that obtained using conventional heating. Hydrolysis by MAH required only 20 min, 48 times faster than with conventional heating. The use of the MAH method in hydrolysis was demonstrated to be reproducible, timesaving and efficient technique in measuring the concentration of urinary TDAs.
    關聯: Talanta 72(6) : p.1527-1532
    Appears in Collections:[嬰幼兒保育系] 期刊論文

    Files in This Item:

    File SizeFormat
    0KbUnknown1016View/Open


    All items in CNU IR are protected by copyright, with all rights reserved.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback