Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/9899
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    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/9899


    Title: PTA治療骨質壞死症之評估
    Authors: 李國榮
    Contributors: 生物科技系
    Date: 2008
    Issue Date: 2009-02-20 11:43:08 (UTC+8)
    Publisher: 台南縣：嘉南藥理科技大學生物科技系
    Abstract: 骨質壞死症(Osteonecrosis)主要的成因是成骨細胞(Osteoblast ) 及破骨細胞(Osteoclast ) 生長不平衡所致。由於PTA 為了具有促進細胞增生的功能，我們試圖利用DNA重組的方式，將PTA基因的構築至具有四環黴素(tetracycline)誘發表現及抗新黴素篩選標記載體( gene vector )，此載體往後可用以對小鼠成骨細胞(Osteoblast ) 及破骨細胞(Osteoclast )進行基因轉殖，分別構築可過渡表現前胸腺素之成骨細胞(Osteoblast ) 及破骨細胞(Osteoclast )，吾人將可藉此胞細胞來探討PTA對細胞分化增生的影響，以評估前胸腺素治療骨質壞死症之可行性。
    Relation: 計畫編號：CN9721
    Appears in Collections:[Dept. of Biotechnology (including master's program)] Chna Project

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