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    Title: 奈米微粒皮膚暴露評估技術探討
    Investigation on Skin Exposure Assessment Technique of Nanoparticles
    Authors: 林維炤
    Contributors: 化妝品應用與管理系
    Keywords: 奈米顆粒
    percutaneous absorption
    Date: 2006
    Issue Date: 2008-11-21 10:34:54 (UTC+8)
    Publisher: 行政院勞工委員會勞工安全衛生研究所
    Abstract: 本研究已建立奈米銀之經皮吸收測定技術, 並評估奈米銀在不同基質下的經皮吸收速率,研究結果顯示對於不同粒徑的奈米銀而言,在18 小時的經皮吸收實驗評估中,均未發現明顯的滲透現象,貼布剝除實驗結果則顯示,在兩小時的皮膚暴露後,奈米銀可以到達第 10~ 20 層之角質層。此外,由工廠訪視的結果可以瞭解,目前台灣製造生產奈米銀的工廠極少。
    In this study, the percutaneous absorption system of nanoparticles, especially for silver nanoparticle, is well established . The eightteen hours skin absorption evalution of silver nanoparticles by diffusion cell method shown that there is no significantly absorption. The 2 hours test with tape stripping method shows that the nanoparticles just spread at layer 1 and layer 2.
    Relation: 計畫編號:IOSH95-H103
    Appears in Collections:[Dept. of Cosmetic Science and institute of cosmetic science] Other Projects

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