| 摘要: | 現今的消費者使用乾燥製品的情形相
當普遍，就經濟上與方便性而言，其具有
可增加製品的架貯期、減少包裝、降低價
格與改善操作特性等優點。本研究中，乾
燥之蕃茄粉末混合適當的賦形劑經壓製成
為咀嚼錠或快速溶解之錠劑。接著評估其
崩散劑性質—錠劑崩散時間與受壓破裂壓
力；結果顯示，崩散劑的種類、添加模式、
添加濃度與相對密度顯著影響錠劑的崩散
時間，但對錠劑受壓破裂壓力的影響則不
顯著。
Dry products have a high level of
popularity with today’s consumers.
Dry mixes are economical and
convenient with increased shelf-life,
reduced packaging, decreased cost
and improved handling properties. In
the study, the dried tomato powder
combined with the appropriated
excipients was pressed into chewable
or a quick dissolve tablet dosage
form. The disintegrant properties –
tablet disintegration time and
crushing strength were evaluated.
The results show that the kinds of
disintegrants, the mode of addition
of disintegrants, disintegrant
concentration and relative density
had a significant impact on the
disintegration time, but not on the
crushing strength. |
