含植酸和果酸之美白化粧品的液相層析影響條件探討

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Title:	含植酸和果酸之美白化粧品的液相層析影響條件探討 The development of analytical method for whitening...
Authors:	楊舒伃 Shu-Yu Yang
Contributors:	李淵博嘉南藥理科技大學：化妝品科技研究所
Keywords:	美白化粧品果酸液相層析植酸 whitening cosmetics fruit acid phytic acid
Date:	2005
Issue Date:	2008-10-31 16:14:42 (UTC+8)
Abstract:	本研究目的在於建立植酸、甘醇酸、乳酸、蘋果酸與杏仁酸之混酸溶液之分析方法。研究中針對管柱的種類、移動相之種類與組成、移動相之流速等因素。對分析物層析結果之影響進行探討，以找到最適化的分離條件。研究中先對分析物個別分析，找到適當的條件再進行混酸之分析。研究結果發現以Discovery® C18 (250×4.6mm，5μm)為固定相，磷酸緩衝液（pH2）和甲醇之混合溶液（95：5）為移動相，流速為0.5 ml/min時，可得到最佳的分離結果。此方法應可應用之實際樣品之分析。 The aim of this research is to establish a analytical method for the determination of phytic acid , glycolic acid , lactic acid , malic acid and mandelic acid in cosmetics.The following factors were considered in this research；column type , pH buffer and organic modifier in the mobile phase and the flow rate of mobile phase. The use of Discovery® C18 column as the stationary phase and a mixture of phosphate buffer(pH2 ) and methanol (95: 5) should be a better choice for the determination of phytic acid and fruit acid in cosmetics. The results could be applied to the determination of phytic acid and fruit acid in real sample.
Relation:	校內馬上公開，校外一年後公開
Appears in Collections:	[Dept. of Cosmetic Science and institute of cosmetic science] Dissertations and Theses

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