Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/34959
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    Title: 以內質網壓力調控nucleobindin-2表現的機制來篩選第二型糖尿病的天然物及臨床用藥
    Using the Mechanism of Endoplasmic Reticulum Stress-Induced Nucleobindin-2 Expression to Screen Natural Products and Clinical Drugs for Type 2 Diabetes
    Authors: 洪瑞祥
    黃溫雅
    吳明娟
    王智揚
    Contributors: 嘉南藥理大學生物科技系(含碩士班)
    Keywords: 內質網壓力
    Nucleobindin-2
    Glucose transporter 2
    肝癌
    轉錄組定序
    第二型糖尿病
    XBP-1
    保健食品
    Endoplasmic reticulum stress
    Nucleobindin-2
    Glucose transporter 2
    Hepatocellular carcinoma
    RNA sequencing
    Type 2 diabetes
    XBP-1
    healthy food.
    Date: 2023
    Issue Date: 2025-01-07 15:00:20 (UTC+8)
    Abstract: 研究指出代謝性疾病人數逐年增加如肥胖及第二型糖尿病,此外在許多研究指出NUCB-2與癌症發展及第二型糖尿病有高度相關性,然而雖然知道NUCB-2與第二型糖尿病有關,但是詳細的機制或是訊息傳遞路徑尚未清楚,因此本實驗直接發現NUCB-2與可能導致第二型糖尿病的基因,並透過篩選來找出最佳的天然物及目前臨床用藥,給予保健食品開發一個重要的參考依據,並且提供目前針對NUCB-2有關的第二型糖尿病一個較適當的治療用藥資訊。
    Relation: 計畫編號:NSTC112-2637-B041-003
    計畫年度:112
    計畫起訖:2023-08~2024-07
    Appears in Collections:[Dept. of Biotechnology (including master's program)] MOST Project
    [Dept. of Pharmacy] MOST Project

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