Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/34889
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    標題: Medium-term surgical outcomes and health-related quality of life after laparoscopic vs open colorectal cancer resection: SF-36 health survey questionnaire
    作者: Hung, Chao-Ming
    Hung, Kuo-Chuan
    Shi, Hon-Yi
    Su, Shih-Bin
    Lee, Hui-Ming
    Hsieh, Meng-Che
    Tseng, Cheng-Hao
    Lin, Shung-Eing
    Chen, Chih-Cheng
    Tseng, Chao-Ming
    Tsai, Ying-Nan
    Chen, Chi-Zen
    Tsai, Jung-Fa
    Chiu, Chong-Chi
    貢獻者: I Shou Univ, E Da Canc Hosp, Dept Gen Surg
    I Shou Univ, Coll Med, Sch Med
    Chi Mei Med Ctr, Dept Anesthesiol
    Chia Nan Univ Pharm & Sci, Dept Hosp & Hlth Care Adm, Coll Recreat & Hlth Management
    Kaohsiung Med Univ, Dept Healthcare Adm & Med Informat
    Natl Sun Yat Sen Univ, Dept Business Management
    Kaohsiung Med Univ Hosp, Dept Med Res
    China Med Univ, China Med Univ Hosp, Dept Med Res
    Chi Mei Med Ctr, Dept Occupat Med
    Chi Mei Med Ctr, Dept Occupat Med
    Southern Taiwan Univ Sci & Technol, Dept Leisure Recreat & Tourism Management
    I Shou Univ, Coll Med
    I Shou Univ, E Da Canc Hosp, Dept Hematol Oncol
    I Shou Univ, E Da Canc Hosp, Dept Gastroenterol & Hepatol
    I Shou Univ, E Da Hosp, Dept Gastroenterol & Hepatol
    I Shou Univ, E Da Canc Hosp, Dept Colon & Rectal Surg
    I Shou Univ, E Da Dachang Hosp, Dept Gastroenterol & Hepatol
    I Shou Univ, E Da Canc Hosp, Dept Med Educ & Res
    Chi Mei Med Ctr, Dept Gen Surg
    關鍵字: Health-related quality of life
    Medium-term result
    Laparoscopic
    Open surgery
    Non-metastatic colorectal cancer
    日期: 2023
    上傳時間: 2024-12-25 11:05:08 (UTC+8)
    出版者: BAISHIDENG PUBLISHING GROUP INC
    摘要: BACKGROUNDPrevious studies that compared the postoperative health-related quality of life (HRQoL) outcomes after receiving laparoscopic resection (LR) or open resection (OR) in patients with colorectal cancer (CRC) have different conclusions.AIMTo explore the medium-term effect of postoperative HRQoL in such patients.METHODSThis study randomized 567 patients undergoing non-metastatic CRC surgery managed by one surgeon to the LR or OR groups. HRQoL was assessed during the preoperative period and 3, 6, and 12 mo postoperative using a modified version of the 36-Item Short Form (SF-36) Health Survey questionnaire, emphasizing eight specific items.RESULTSThis cohort randomly assigned 541 patients to receive LR (n = 296) or OR (n = 245) surgical procedures. More episodes of postoperative urinary tract infection (P < 0.001), wound infection (P < 0.001), and pneumonia (P = 0.048) were encountered in the OR group. The results demonstrated that the LR group subjectively gained mildly better general health (P = 0.045), moderately better physical activity (P = 0.006), and significantly better social function recovery (P = 0.0001) 3 mo postoperatively. Only the aspect of social function recovery was claimed at 6 mo, with a significant advantage in the LR group (P = 0.001). No clinical difference was found in HRQoL during the 12 mo.CONCLUSIONOur results demonstrated that LR resulted in better outcomes, including intra-operative blood loss, surgery-related complications, course of recovery, and especially some health domains of HRQoL at least within 6 mo postoperatively. Patients should undergo LR if there is no contraindication.
    關聯: World Journal of Gastrointestinal Endoscopy, v.15, n.3, pp.163-176
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