Commentary on small-volume biopsy of follicular lymphoma: Practical issues in the molecular era

doi:10.1002/cncy.22742

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Title:	Commentary on small-volume biopsy of follicular lymphoma: Practical issues in the molecular era
Authors:	Chen, Chien-Chin
Contributors:	Ditmanson Med Fdn Chia Yi Christian Hosp, Dept Pathol Natl Cheng Kung Univ, Coll Biosci & Biotechnol, Dept Biotechnol & Bioind Sci Chia Nan Univ Pharm & Sci, Dept Cosmet Sci Natl Chung Hsing Univ, Rong Hsing Res Ctr Translat Med, PhD Program Translat Med
Keywords:	biopsy core needle fine-needle aspiration follicular lymphoma hematology lymphoma
Date:	2024
Issue Date:	2024-12-25 11:05:06 (UTC+8)
Publisher:	WILEY
Abstract:	Follicular lymphoma (FL) is a common subtype of non-Hodgkin lymphoma derived from germinal center B-cells. Small-volume biopsies (SVBs), including fine-needle aspiration, needle core biopsy, and cell blocks, are often used for the assessment of patients with FL. Recently, Fitzpatrick et al. found that additional biopsies were frequently needed to supplement SVB for the initial diagnosis of FL. However, regardless of the type of SVB used, additional biopsies were usually not necessary for assessments for transformed or recurrent FL. Their multi-institutional study reflects the fact that SVB may be sufficient for clinical decision-making in these medical settings, although surgical excision is the gold standard for a definitive diagnosis of FL. With ancillary tests and advances in molecular testing, SVB has become increasingly popular and helpful, although there are practical limitations.
Relation:	Cancer Cytopathology, v.132, n.3, pp.136-138
Appears in Collections:	[Offices] 456

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