Inverse Probability of Treatment Weighting in 5-Year Quality-of-Life Comparison among Three Surgical Procedures for Hepatocellular Carcinoma

doi:10.3390/cancers15010252

Chia Nan University of Pharmacy & Science Institutional Repository > 行政單位 > 456 > Item 310902800/34792

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/34792

標題:	Inverse Probability of Treatment Weighting in 5-Year Quality-of-Life Comparison among Three Surgical Procedures for Hepatocellular Carcinoma
作者:	Chang, Der-Ming Chen, Yu-Fu Chen, Hong-Yaw Chiu, Chong-Chi Lee, King-Teh Wang, Jhi-Joung Sun, Ding-Ping Lee, Hao-Hsien Shiu, Yu-Tsz Chen, I-Te Shi, Hon-Yi
貢獻者:	Yuans Gen Hosp, Dept Surg, Div Digest Surg Yuans Gen Hosp, Dept Clin Educ & Res I Shou Univ, Coll Med, Sch Med E Da Canc Hosp, Dept Med Educ & Res Kaohsiung Med Univ Hosp, Dept Surg, Div Hepatobiliary Surg Kaohsiung Med Univ, Dept Healthcare Adm & Med Informat Chi Mei Med Ctr, Dept Med Res Chi Mei Med Ctr, Dept Gen Surg Chia Nan Univ Pharm & Sci, Dept Food Sci & Technol Natl Sun Yat Sen Univ, Dept Business Management Kaohsiung Med Univ Hosp, Dept Med Res China Med Univ, China Med Univ Hosp, Dept Med Res
關鍵字:	quality of life hepatocellular carcinoma surgery generalized estimating equations
日期:	2023
上傳時間:	2024-12-25 11:03:32 (UTC+8)
出版者:	MDPI
摘要:	Simple Summary In patients who had undergone resection for hepatocellular carcinoma (HCC), scores for most quality-of-life (QOL) subscales were significantly improved by 6 months after resection; QOL scores then remained stable for the rest of the 5-year period of this study. The QOL improvements after laparoscopic surgery or robotic surgery were much larger than improvements after open surgery. Between the 2nd and 5th year postsurgery, however, QOL improvements were larger in robotic surgery patients compared to laparoscopic surgery patients. This prospective longitudinal cohort study analyzed long-term changes in individual subscales of quality-of-life (QOL) measures and explored whether these changes were related to effective QOL predictors after hepatocellular carcinoma (HCC) surgery. All 520 HCC patients in this study had completed QOL surveys before surgery and at 6 months, 2 years, and 5 years after surgery. Generalized estimating equation models were used to compare the 5-year QOL among the three HCC surgical procedures. The QOL was significantly (p < 0.05) improved at 6 months after HCC surgery but plateaued at 2-5 years after surgery. In postoperative surveys, the effect size was largest in the nausea and vomiting subscales in patients who had received robotic surgery, and the effect size was smallest in the dyspnea subscale in patients who had received open surgery. It revealed the following explanatory variables for postoperative QOL: surgical procedure type, gender, age, hepatitis C, smoking, tumor stage, postoperative recurrence, and preoperative QOL. The comparisons revealed that, when evaluating QOL after HCC surgery, several factors other than the surgery itself should be considered. The analysis results also implied that postoperative quality of life might depend not only on the success of the surgical procedure, but also on preoperative quality of life.
關聯:	Cancers, v.15, n.1, Article 252
显示于类别:	[行政單位] 456

文件中的档案:

档案	描述	大小	格式	浏览次数
index.html		0Kb	HTML	5	检视/开启

在CNU IR中所有的数据项都受到原著作权保护.

TAIR相关文章

数据加载中.....