Malignant transformation of oral potentially malignant disorders in Taiwanese indigenous peoples: A nationwide retrospective cohort study

CNU IR > College of Smart Living > Dept. of Hospital and Health (including master's program) > Periodical Articles > Item 310902800/34645

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/34645

题名:	Malignant transformation of oral potentially malignant disorders in Taiwanese indigenous peoples: A nationwide retrospective cohort study
作者:	Chen, I-An Chiu, Sheng-Fu Hung, Kuo-Chuan Yu, Chia-Hung Chen, Yi-Chen Ho, Chung-Han Chiang, Wei-Fan Chang, Ying-Jen
贡献者:	Chi Mei Hospital Chia Nan University of Pharmacy & Science, Department of Hospital and Health Care Administration Chi Mei Hospital Southern Taiwan University of Science & Technology National Yang Ming Chiao Tung University Chia Nan University of Pharmacy & Science, Department of Recreation and Health-Care Management
关键词:	verrucous carcinoma hyperplasia
日期:	2022
上传时间:	2023-12-11 14:02:26 (UTC+8)
出版者:	LIPPINCOTT WILLIAMS & WILKINS
摘要:	Malignant transformation of oral potentially malignant disorders (OPMDs) is a potential cause of oral cancer. Currently, there is no research investigating the rate of malignant transformation of OPMDs into oral cancer in indigenous Taiwanese peoples. This study aimed to retrospectively investigate whether ethnicity (indigenous vs non-indigenous people) plays a role in increasing the malignant transformation rate of OPMDs into oral cancer. This study used data from the oral mucosal screening database and the Cancer Registry File, both of which originated from the National Health Insurance Research Database. We matched the baseline characteristics to control for confounding factors between indigenous peoples and non-indigenous peoples (17,768 indigenous subjects vs 71,072 non-indigenous subjects; 1:4 match) and compared the 2 cohorts. After matching for confounding factors such as age, sex, habits, and OPMD subtype, the malignant transformation rate was not statistically higher for indigenous people than for non-indigenous people. We also discovered that indigenous people with oral verrucous hyperplasia might have a higher chance of malignant transformation into oral cancer than the non-indigenous cohort. We conclude that ethnicity is not a risk factor for the malignant transformation of OPMDs into oral cancer; however, indigenous people with oral verrucous hyperplasia need to pay special attention and are suggested to undergo regular follow-ups for the occurrence of oral cancer.
關聯:	MEDICINE, v.101, n.46, p31910
显示于类别:	[Dept. of Hospital and Health (including master's program)] Periodical Articles [Dept. of Recreation and Health-Care Management] Periodical Articles

文件中的档案:

档案	描述	大小	格式	浏览次数
index.html		0Kb	HTML	362	检视/开启
MD.0000000000031910.pdf		649Kb	Adobe PDF	94	检视/开启

在CNU IR中所有的数据项都受到原著作权保护.

TAIR相关文章

数据加载中.....