Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/34578
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    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/34578


    Title: The first invasive Candida auris infection in Taiwan
    Authors: Tsai, Yu-Te
    Lu, Po-Liang
    Tang, Hung-Jen
    Huang, Chung-Hao
    Hung, Wei-Chun
    Tseng, Yi-Ting
    Lee, Kun-Mu
    Lin, Shang-Yi
    Contributors: Kaohsiung Medical University
    Kaohsiung Medical University Hospital
    Chi Mei Hospital
    Department of Health and Nutrition, Chia Nan University of Pharmacy & Science
    Keywords: care-unit
    yeast
    identification
    epidemiology
    resistant
    emergence
    Date: 2022
    Issue Date: 2023-12-11 13:58:51 (UTC+8)
    Publisher: TAYLOR & FRANCIS LTD
    Abstract: Candida auris, a multidrug resistant pathogenic yeast, has spread worldwide and caused several outbreaks in healthcare settings. Here, we report the first case of C. auris candidemia in Taiwan in a patient with a two-month history of hospitalization in Vietnam. We performed further investigation on the isolate from the present case as well as the previously reported C. auris isolate identified from a wound in 2018 in Taiwan, which was the first case reported in Taiwan. Both C. auris isolates were found to be susceptible to fluconazole, amphotericin B, and echinocandins. Additionally, mutations in ERG11 or FKS1 were not detected in either isolate. Microsatellite genotyping revealed that both isolates belonged to the South Asian clade. In recent years, C. auris has emerged as a global concern, and differences in clades and susceptibility patterns mandate further awareness and systematic surveillance.
    Relation: Emerging Microbes & Infections, v.11, n.1, pp.1867-1875
    Appears in Collections:[Dept. of Health and Nutrition (including master's program)] Periodical Articles

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