Association of peripheral nerve blocks with patient-reported quality of recovery in female patients receiving breast cancer surgery: a systematic review and meta-analysis of randomized controlled studies

CNU IR > College of Smart Living > Dept. of Hospital and Health (including master's program) > Periodical Articles > Item 310902800/34554

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/34554

Title:	Association of peripheral nerve blocks with patient-reported quality of recovery in female patients receiving breast cancer surgery: a systematic review and meta-analysis of randomized controlled studies
Authors:	Hung, Kuo-Chuan Ko, Ching-Chung Hsu, Chih-Wei Pang, Yu-Li Chen, Jen-Yin Sun, Cheuk-Kwan
Contributors:	Chi Mei Hospital Department of Hospital and Health Care Administration, Chia Nan University of Pharmacy & Science Chi Mei Hospital Department of Health and Nutrition, Chia Nan University of Pharmacy & Science National Sun Yat Sen University Chang Gung Memorial Hospital Chang Gung University E-Da Hospital I Shou University
Keywords:	modified radical-mastectomy postoperative quality general-anesthesia pain score analgesia relief
Date:	2022
Issue Date:	2023-12-11 13:57:35 (UTC+8)
Publisher:	SPRINGER
Abstract:	Purpose This systematic review and meta-analysis investigated the impact of peripheral nerve blocks (PNBs) on patient-reported quality of recovery (QoR) following breast cancer surgery. Source Medline, EMBASE, Cochrane Library, and Google scholar databases were searched for randomized controlled trials (RCTs) comparing the QoR with or without PNBs in patients receiving breast cancer surgery from inception to September 2021. Using a random effects model, the primary outcome was total scores of postoperative QoR scales (i.e., QoR-15 and QoR-40). Principal findings Eight RCTs (QoR-15, n = 4; QoR-40, n = 4) involving 653 patients published from 2018 to 2021 were included. For the QoR-40 scale, pooled results revealed a significantly higher total score (mean difference [MD], 12.8 [8.2%]; 95% confidence interval [CI], 10.6 to 14.9; I-2 = 59%; five RCTs; n = 251) and scores on all subscales, except psychological support, in the PNB group than in controls at 24 hr after surgery. For the QoR-15 scale, pooled results also showed favorable QoR (MD, 7.7 [5.2%]; 95% CI, 4.9 to 10.5; I-2 = 75%; four RCTs; n = 402) in the PNB group at 24 hr after surgery. Sensitivity analysis showed no effect on the QoR-40 score and the difference in total QoR-15 score was no longer significant when a single trial was omitted. The use of PNBs was associated with a significantly lower opioid consumption and risk of postoperative nausea and vomiting without significant differences in the pain score between the two groups. Conclusion Our results verified the efficacy of PNBs for enhancing postoperative QoR using two validated patient-reported tools in female patients receiving breast cancer surgery under general anesthesia. Study registration PROSPERO (CRD42021272575); first submitted 9 August 2021.
Relation:	CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE, v.69, pp.1288–1299
Appears in Collections:	[Dept. of Hospital and Health (including master's program)] Periodical Articles [Dept. of Health and Nutrition (including master's program)] Periodical Articles

Files in This Item:

File	Description	Size	Format
index.html		0Kb	HTML	256	View/Open
s12630-022-02295-0.pdf		2328Kb	Adobe PDF	88	View/Open

Loading...