Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/34470
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    Title: Production of a new triterpenoid disaccharide saponin from sequential glycosylation of ganoderic acid A by 2 Bacillus glycosyltransferases
    Authors: Chang, Te-Sheng
    Chiang, Chien-Min
    Wu, Jiumn-Yih
    Tsai, Yu-Li
    Ting, Huei-Ju
    Contributors: Natl Univ Tainan, Dept Biol Sci & Technol
    Chia Nan Univ Pharm & Sci, Dept Pharm
    Natl Quemoy Univ, Dept Food Sci
    Keywords: ganoderic acid A
    glycosyltransferase
    triterpenoid
    glucosides
    saponin
    Date: 2021
    Issue Date: 2023-11-11 11:55:41 (UTC+8)
    Publisher: OXFORD UNIV PRESS
    Abstract: Ganoderic acid A (GAA) is a lanostane-type triterpenoid, isolated from medicinal fungus Ganoderma lucidum, and possesses multiple bioactivities. In the present study, GAA was sequentially biotransformed by 2 recently discovered Bacillus glycosyltransferases (GT), BtGT_16345 and BsGT110, and the final product was purified and identified as a new compound, GAA-15,26-O-beta-diglucoside, which showed 1024-fold aqueous solubility than GAA.
    關聯: BIOSCI BIOTECH BIOCH, v.85, n.3, pp.687-690
    显示于类别:[Dept. of Pharmacy] Periodical Articles

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