Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/34464
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    Title: Insights into the major phenolic acids in Perilla frutescens obtained by a sustainable procedure
    Authors: Yang, Yu-Chiao
    Wang, Chia-Sui
    Wei, Ming-Chi
    Contributors: Kaohsiung Med Univ, Dept & Grad Inst Pharmacol
    Kaohsiung Med Univ Hosp, Dept Med Res
    Chia Nan Univ Pharm & Sci, Dept Environm Engn & Sci
    Keywords: Perilla frutescens
    rosmarinic acid
    ultrasound-assisted supercritical CO2 extraction
    green procedure
    Fick's second diffusion model
    thermodynamic parameters
    Date: 2021
    Issue Date: 2023-11-11 11:54:24 (UTC+8)
    Publisher: ELSEVIER SCIENCE INC
    Abstract: This research was performed to evaluate the efficiency of ultrasound in obtaining the total extract, caffeic acid and rosmarinic acid from Perilla frutescens using supercritical CO2 (USCCO2) extraction. Compared with traditional heat-reflux, ultrasonic-assisted and SCCO2 extractions, the USCCO2 technique decreased the extraction duration (1.12-1.92 times) and the consumption of solvent (1.90-285.71 times) at lower extraction temperatures and obtained a higher yield from the plant matrix. Furthermore, a second-order kinetic model and Fick's second diffusion model were implemented to ascertain the extraction rate constant, equilibrium concentration, initial extraction rate, effective diffusion coefficient, mass transfer coefficient, Biot number, equilibrium constant and thermodynamic parameters of the USCCO2 and SCCO2 dynamic extractions of rosmarinic acid from P. frutescens. These results provide valuable insights into the kinetic and mass transfer behaviors that occur during the USCCO2 and SCCO2 procedures and explain the reasons for the better extraction efficiency of the former procedure. (C) 2021 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
    Relation: J IND ENG CHEM, v.96, pp.109-120
    Appears in Collections:[Dept. of Environmental Engineering and Science (including master's program)] Periodical Articles

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