Evaluation of factors associated with en bloc colonic underwater endoscopic mucosal resection

doi:10.1002/aid2.13207

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Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/34146

Title:	Evaluation of factors associated with en bloc colonic underwater endoscopic mucosal resection
Authors:	Chen, Chien-An Ho, Chung-Han Hsieh, Ping-Hsin
Contributors:	Chi Mei Med Ctr, Dept Internal Med, Div Hepatogastroenterol Chi Mei Med Ctr, Dept Internal Med Chi Mei Med Ctr, Dept Med Res Chia Nan Univ Pharm & Sci, Dept Hosp & Hlth Care Adm
Keywords:	endoscopic mucosal resection (EMR) endoscopic therapy new endoscopic technique
Date:	2021
Issue Date:	2022-11-18 11:25:55 (UTC+8)
Publisher:	Wiley
Abstract:	Underwater endoscopic mucosal resection (UEMR) is a relatively simple and safe method for resecting sessile colorectal polyps without a submucosal injection. Only around 1000 UEMRs have been reported in a few studies, and none of the previous studies directly evaluated the factors associated with a successful en bloc resection. We retrospectively evaluated the factors associated with a successful en bloc resection using UEMR from 160 patients between August 2015 and November 2017. Of 173 polyps removed with UEMR, 141 polyps (81.5%) were removed en bloc. Univariable analysis showed that polyp size >= 20 mm (OR: 0.047, 95% CI: 0.014-0.162, P < .001), prior treatment (OR: 0.297, 95% CI: 0.135-0.655, P = .003), and polyp morphology (flat vs sessile) (OR: 0.111, 95% CI: 0.025-0.482, P = .003) were the significant factors for en bloc resection. Multivariate analysis showed that polyp size >= 20 mm (OR: 0.053, 95% CI: 0.015-0.194, P < .001), prior treatment (OR: 0.313, 95% CI: 0.118-0.832, P = .020), and polyp morphology (flat vs sessile) (OR: 0.095, 95% CI: 0.019-0.469, P = .004) were still significant. The rate of adverse events was 3.5% (n = 6) and included delayed hemorrhages (n = 2, 1.2%), muscle defects requiring endoscopic clipping (n = 3, 1.7%), and delayed perforations (n = 1, 0.6%). Polyp size < 20 mm, without prior treatment, and sessile polyp morphology were significantly associated with en bloc UEMR.
Relation:	Advances In Digestive Medicine, v.8, n.3, pp.8
Appears in Collections:	[Dept. of Hospital and Health (including master's program)] Periodical Articles

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