Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/34059
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    Title: A new macrocyclic diterpenoid fromAnisomeles indica
    Authors: Chao, Chen-Liang
    Huang, Hui-Chi
    Ding, Hsiou-Yu
    Lai, Jenn-Haung
    Lin, Hang-Ching
    Chang, Wen-Liang
    Contributors: Sinphar Pharm Co Ltd, Res & Dev Ctr, Ilan
    China Med Univ, Dept Chinese Pharmaceut Sci & Chinese Med Resourc
    Chia Nan Univ Pharm & Sci, Dept Cosmet Sci
    Triserv Gen Hosp, Dept Med, Rheumatol Immunol & Allergy
    Natl Def Med Ctr, Sch Pharm
    Keywords: Anisomeles indica
    labiatae
    4 beta
    5 beta-dihydroxyovatodiolide
    anti-arthritis activity
    Date: 2020
    Issue Date: 2022-11-18 11:22:11 (UTC+8)
    Publisher: Taylor & Francis Ltd
    Abstract: A new macrocyclic diterpenoid, 4 beta,5 beta-dihydroxyovatodiolide (1), together with twenty-two known compounds (2-23) were isolated from the MeOH extract of the dried aerial parts ofAnisomeles indica(L.) O. Kuntze (Labiatae). The structure of1was established on the basis of spectral evidence. Phenylethanoids, acteoside (5) and isoacteoside (6) showed significant inhibitory to IL-2 secretion of with respect to phorbol myristate acetate and anti-CD28 monoclonal antibody co-stimulated activation of human peripheral blood T cells.
    Relation: Natural Product Research, v.34, n.19, pp.9
    Appears in Collections:[Dept. of Cosmetic Science and institute of cosmetic science] Periodical Articles

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