Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/33611
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    CNU IR > Pharmacy and Science > 2017 >  Item 310902800/33611
    Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/33611


    Title: 大黃抗發炎之活性成分探討
    Authors: 黃筌韋
    邱峻邑
    吳佩珊
    丁秀玉
    吳明娟
    Contributors: 藥學系
    生物科技系
    化粧品應用與管理系
    Date: 2017
    Issue Date: 2022-01-25 14:53:05 (UTC+8)
    Abstract: 掌葉大黃(Rheum palmatum),屬於蓼科大黃屬,以乾燥其莖根入藥,具有涼血解毒、逐瘀通經的功效,用於實熱便祕,積滯腹痛,瀉痢不爽,濕熱黃疸,上消化道出血等症狀。常見成分有大黃酚、大黃素、大黃酸等??物質,具有輕瀉效果。本研究主要利用脂多醣(Lipopolysaccharide)刺激的小鼠巨噬細胞(RAW 264.7)作為檢測平台,探討大黃抗發炎的有效成分。結果顯示大黃之成分:D178 (結構未知) 和D179(結構未知) 可有效抑制LPS 誘導之一氧化氮(NO)的生成,並且不具細胞毒性。因此D178、D179 為大黃主要的抗發炎成分。
    Relation: 2017 第十一屆嘉南藥理大學藥理學院師生研究成果發表會,起迄日:2017/05/02-2017/05/04
    Appears in Collections:[Pharmacy and Science] 2017

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