Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/33035
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    標題: 市售奈米銀水溶液抗菌效果之研究-以A廠為例
    The antibacterial performance of commercial nano silver spray products- the A factory as an example
    作者: 林敬峰
    貢獻者: 環境工程與科學系
    陳世雄
    關鍵字: 奈米銀粒子
    抗菌
    nano silver
    DLS
    TEM
    UV-VIS
    日期: 2019
    上傳時間: 2020-12-09 14:44:55 (UTC+8)
    摘要: 本研究發現目前市面上有許多的奈米銀產品是以化學合成(硝酸銀、碘化銀)方法生產製造,並且生產製程中添加大量的介面活性劑造成產品含雜質成份太高,奈米銀水溶液之品質差異大,而A廠生產研發技術採用綠色生產製程以銀為原料直接於純水合成奈米銀顆粒,所生產之奈米銀水溶液品質穩定,具粒徑分布窄、類球狀顆粒形態,且抗菌效果經SGS檢測,證實對大腸桿菌、金黃色葡萄球菌、綠膿桿菌、白色念珠菌及克雷白氏肺炎菌等均具有99.9%的抗菌效果。
    本次研究方法使用A公司奈米銀水溶液與其他國內廠商奈米銀水溶液進行分析比較,採用粒徑分析(DLS)、穿透式電子顯微鏡(TEM)、可見光譜(UV-vis)進行分析比對後,奈米銀水溶液產品與國內市售他牌存在以下之差距: 一、奈米銀水溶液粒子標示之濃度、粒徑不實,二、產品內容界面活性劑添加量及化學成分標示不清。三、產品規格及價格差異大,四、奈米銀離子產品充斥市場,易造成產品混淆,五、國內廠商無法自行大量生產。對於A廠奈米銀水溶液產品及製備技術已可與現有廠商競爭並由產品檢測抗菌結果得知,A廠奈米銀水溶液產品具備優異抗菌性能並且保有放量生產之能力。
    The chemical reduction method (AgNO3 and AgI) were used for commercial nano silver disperse production. The poor quality nano silver disperse with chemical surfactants additive decreased the antibacterial performance of products. In the case of nano silver disperse of a factory, the nano silver disperse was produced in the pure water and no solvent additive with a green process design. The nano products presents a narrow particle size distribution and sphere shape. The antibacterial performance were confirmed by the SGS with the E Coli, Staphylococcus aureus, Pseudomonas, Candida albicans, and Candida albicans antibacterial testing.
    In this investigation, the comparison with a factory nano silver products and other commercial products were made by DLS, TEM and UV- vis spectrum analysis. The conclusions of those comparisons were made as following: 1. The concentration and particle size of commercial products are not inaccurate. 2. The chemicals and surfactant additive were added into products. 3. Large different in the specification and price. 4. Nano silver ion products disturbed the market. 5. Nano silver particle disperse product is difficult to scale up. It is concluded that the products of factory a can be competed with the commercial products and presented a good antibacterial quality for application. The optimum production rate and price can be also achieved in this technology of factory A.
    關聯: 電子全文公開日期:2024-07-19
    學年度:107,84頁
    顯示於類別:[環境工程與科學系(所)] 博碩士論文

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