含溫度感應型材料之緩釋型奈米纖維及其製法

CNU IR > Pharmacy and Science > Dept. of Cosmetic Science and institute of cosmetic science > Patent > Item 310902800/32871

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题名:	含溫度感應型材料之緩釋型奈米纖維及其製法 Sustained-Release Nanofiber Containing Thermo-Sensitive Material and Method for Making The Same
作者:	李佳芬張羽萱
贡献者:	化粧品應用與管理系
日期:	2016-12-21
上传时间:	2020-12-01 14:17:53 (UTC+8)
摘要:	本發明係有關於一種含溫度感應型材料之緩釋型奈米纖維及其製法，其製法包括提供複數個乳膠顆粒；將一溫度感應型材料溶解於一甲醇溶液，再加入複數個乳膠顆粒混合，以形成一混合溶液；以及將混合溶液利用靜電紡絲法製成一奈米纖維，並置於110℃進行交聯反應，得到一含溫度感應型材料之緩釋型奈米纖維；所述複數個乳膠顆粒為實心poly(MMA-MAA)/poly(NIPAAm-MAA)乳膠顆粒或空心poly(NIPAAm-MAA)乳膠顆粒。 The invention relates to a sustained-release nanofiber containing a thermo-sensitive material and a method for making the same. The method comprises preparing a plurality of latex particles; dissolving a thermo-sensitive material in a methanol solution and adding the plurality of latex particles to form a mixed solution; and then making the mixed solution into a nanofiber by electrospinning and using a heat-drying way to crosslink the nanofiber at the temperature of?110 ℃, so as to make a sustained-release nanofiber containing the thermo-sensitive material. The plurality of latex particles are solid poly(MMA-MAA)/poly(NIPAAm-MAA) latex particles or hollow poly(NIPAAm-MAA) latex particles.
關聯:	專利編號：I562802 申請號：104133725 國際分類號：A61K-009/70(2006.01);A61K-047/32(2006.01) 專利公報：43卷36期
显示于类别:	[Dept. of Cosmetic Science and institute of cosmetic science] Patent

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