Timing of follow-up blood cultures for community-onset bacteremia

doi:10.1038/s41598-019-51032-z

Chia Nan University of Pharmacy & Science Institutional Repository > 藥理學院 > 保健營養系(所) > 期刊論文 > Item 310902800/32674

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://ir.cnu.edu.tw/handle/310902800/32674

標題:	Timing of follow-up blood cultures for community-onset bacteremia
作者:	Lee, Ching-Chi Yang, Chao-Yung Hsieh, Chih-Chia Hong, Ming-Yuan Lee, Chung-Hsun Hung-Jen Tang(湯宏仁) Ko, Wen-Chien
貢獻者:	Tainan Sin Lau Hosp, Dept Adult Crit Care Med Chang Jung Christian Univ, Coll Hlth Sci, Grad Inst Med Sci Natl Cheng Kung Univ Hosp, Dept Emergency Med, Tainan, Taiwan Natl Cheng Kung Univ, Med Coll, Dept Med Chi Mei Med Ctr, Dept Med Chia Nan Univ Pharm & Sci, Dept Hlth & Nutr Natl Cheng Kung Univ Hosp, Dept Internal Med
關鍵字:	GRAM-NEGATIVE BACTEREMIA OUTCOMES ISSUES ADULTS
日期:	2019-10
上傳時間:	2020-07-29 13:54:46 (UTC+8)
出版者:	NATURE PUBLISHING GROUP
摘要:	Bacteremia is associated with high morbidity and mortality, but the utility and optimal timing of follow-up blood cultures (FUBCs) remain undefined. To assess the optimal timing of FUBCs related to appropriate antibiotic therapy (AAT), adults with community-onset bacteremia and FUBCs after bacteremia onset were retrospectively studied during the 6-year period in two hospitals. Based on the time gap between the initiation of AAT and FUBC sampling, 1,247 eligible patients were categorized as FUBCs prior to AAT (65 patients, 5.2%), 0-3 days (202, 16.2%), 3.1-6 days (470, 37.7%), 6.1-9 days (299, 24.0%), and >= 9 days (211, 16.9%) after AAT. The prognostic impact of the growth of the same bacteria in FUBCs on 30-day mortality was evidenced only in patients with FUBCs at 3.1-6 days after AAT (adjusted odds ratio [AOR], 3.75; P < 0.001), not in those with FUBCs prior to AAT (AOR, 2.86; P= 0.25), 0-3 days (AOR, 0.39; P= 0.08), 6.1-9 days (AOR, 2.19; P= 0.32), and >= 9 days (AOR, 0.41; P= 0.41) of AAT, after adjusting independent factors of 30-day mortality recognized by the multivariable regression in each category. Conclusively, persistent bacteremia in FUBCs added prognostic significance in the management of adults with community-onset bacteremia after 3.1-6 days of AAT.
關聯:	Scientific Reports, v.9, 14500
显示于类别:	[保健營養系(所) ] 期刊論文

文件中的档案:

档案	描述	大小	格式	浏览次数
10.1038-s41598-019-51032-z.pdf		1209Kb	Adobe PDF	330	检视/开启
index.html		0Kb	HTML	1161	检视/开启

在CNU IR中所有的数据项都受到原著作权保护.

TAIR相关文章

数据加载中.....