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| 標題: | Prophylactic midurethral sling insertion during transvaginal pelvic reconstructive surgery for advanced prolapse patients with high-risk predictors of postoperative de novo stress urinary incontinence |
| 作者: | Lo, Tsia-Shu
Chua, Sandy
Kao, Chuan Chi
Hsieh, Wu-Chiao
Ming-Ping Wu(吳銘斌)
Tseng, Ling-Hong |
| 貢獻者: | Chang Gung Mem Hosp, Keelung Med Ctr, Dept Obstet & Gynecol
Chang Gung Mem Hosp, Linkou Med Ctr, Dept Obstet & Gynecol, Div Urogynecol
Chang Gung Univ, Sch Med
Cebu Velez Gen Hosp, Cebu Inst Med, Dept Obstet & Gynecol
Chi Mei Fdn Hosp, Dept Obstet & Gynecol, Div Urogynecol & Pelv Floor Reconstruct
Chia Nan Univ Pharm & Sci, Ctr Gen Educ |
| 關鍵字: | De novo stress urinary incontinence
Continent women
Midurethral sling
Pelvic organ prolapse
Predictive factor |
| 日期: | 2019-09 |
| 上傳時間: | 2020-07-29 13:50:00 (UTC+8) |
| 出版者: | SPRINGER LONDON LTD |
| 摘要: | Introduction and hypothesis Our aim was to evaluate the clinical outcome of continent women with high-risk predictors for de novo stress urinary incontinence (SUI) offered prophylactic midurethral sling (MUS) insertion during vaginal pelvic reconstructive surgery (PRS) for advanced pelvic organ prolapse (POP). Materials and methods This was a prospective cohort study in patients with POP stage >= 3 and maximum urethral closure pressure (MUCP) <60 cmH(2)O and functional urethral length (FUL) <2 cm. Patients were divided into PRS and PRS + MUS groups. Surgery commenced with vaginal hysterectomy, application of Uphold (R) and insertion of MUS to the PRS + MUS group. Main outcome measures were incidence of de novo urodynamic stress incontinence (USI), lower urinary tract symptoms (LUTS), quality of life (QoL), and topographic and anatomical relationship of implanted mesh. Results Based on sample size calculation, 40 patients were recruited-20 in each group. Rate of de novo USI in PRS + MUS was 5% objectively and 10% subjectively, while in the PRS it was 50% objectively and 60% subjectively. No significant difference was noted in patient demographics. Intraoperative blood loss was greater for PRS + MUS but was not statistically significant. No organ injuries, mesh exposure, or infections occurred. Postoperatively, MUCP significantly increased from 43.3 +/- 8.9 to 58.5 +/- 19.2 cmH(2)O and FUL from 17.2 +/- 1.9 to 20.3 +/- 3.1 mm in the PRS + MUS group. Residual urine significantly decreased. No patient had bladder outlet obstruction (BOO). Sonographic assessment showed no difference in mesh mobility with urethral kinking observed in 11 (55%) patients with MUS. Conclusion Based on a validated small sample, prophylactic MUS for continent women at high risk for postoperative USI with advanced POP lowers its incidence to 5%. Continence is achieved in 95%. Concern for complications, LUTS, and QoL did not significantly differ. |
| 關聯: | International Urogynecology Journal, v.30, n.9, pp.1541-1549 |
| 顯示於類別: | [通識教育中心] 期刊論文
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