Long-term mortality in older adults with chronic pain: a nationwide population-based study in Taiwan

doi:10.1007/s41999-019-00228-7

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Title:	Long-term mortality in older adults with chronic pain: a nationwide population-based study in Taiwan
Authors:	Tsai, Meng-Hsiu Tsay, Wen-Ing Her, Shwu-Huey Chung-Han Ho(何宗翰) Chen, Yi-Chen Hsu, Chien-Chin Wang, Jhi-Joung Huang, Chien-Cheng
Contributors:	Chi Mei Med Ctr, Palliat Care Ctr Chi Mei Med Ctr, Dept Geriatr & Gerontol Minist Hlth & Welf, Food & Drug Adm, Div Controlled Drugs Chi Mei Med Ctr, Dept Med Res Chia Nan Univ Pharm & Sci, Dept Hosp & Hlth Care Adm Chi Mei Med Ctr, Dept Emergency Med Southern Taiwan Univ Sci & Technol, Dept Biotechnol Southern Taiwan Univ Sci & Technol, Allied AI Biomed Ctr Southern Taiwan Univ Sci & Technol, Dept Sr Serv Natl Cheng Kung Univ, Coll Med, Dept Environm & Occupat Hlth
Keywords:	Chronic pain Long-term Mortality Older
Date:	2019-10
Issue Date:	2020-07-29 13:49:28 (UTC+8)
Publisher:	SPRINGER
Abstract:	Purpose This study was conducted to clarify the long-term mortality in the older population with chronic pain (CP), which is still unclear. Methods We identified 17,568 older participants (aged >= 65 years) with CP and an identical number of comparison cohort without CP matched 1:1 by age and sex between 1996 and 2000 from the Taiwan National Health Insurance Research Database. Causes of CP, underlying comorbidities, living areas, and mortality were collected for analyses. The long-term mortality and the causes of mortality were compared between the two cohorts through follow-up since 2000 until 2015. Results The mean age (+/- standard deviation) was 73.5 +/- 5.7 years, and female participants comprised 55.1% in both cohorts. The most common causes of CP were osteoarthritis (24.2%), spinal disorders (22.4%), peripheral vascular diseases (14.0%), and osteoporosis (9.5%). Older participants with CP had an increased rate of long-term mortality compared to that among their counterparts without CP after adjusting for the underlying comorbidities and the causes of CP (adjusted hazard ratio [AHR]: 1.18; 95% confidence interval [CI] 1.14-1.21). The increased mortality rate was observed even after the follow-up of 6 years (AHR 1.15; 95% CI 1.10-1.20). No significant difference was observed in the causes of mortality between the two cohorts. The most common cause of mortality was malignancy, followed by cardiovascular and cerebrovascular diseases. Conclusions Chronic pain was associated with an increased rate of long-term mortality in the older population. Early detection and intervention for treating CP are suggested for this population.
Relation:	European Geriatric Medicine, v.10, n.5, pp.777-784
Appears in Collections:	[Dept. of Hospital and Health (including master's program)] Periodical Articles

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