The multifaceted link between inflammation and human diseases

doi:10.1002/jcp.26479

CNU IR > College of Smart Living > Dept. of Hospital and Health (including master's program) > Periodical Articles > Item 310902800/32326

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Title:	The multifaceted link between inflammation and human diseases
Authors:	Rajendran, Peramaiyan Chen, Ya-Fang Chen, Yu-Feng Chung, Li-Chin Tamilselvi, Shanmugam Shen, Chia-Yao Day, Cecilia Hsuan Chen, Ray-Jade Viswanadha, Vijaya P. Kuo, Wei-Wen Huang, Chih-Yang
Contributors:	China Med Univ, Grad Inst Basic Med Sci Taichung Vet Gen Hosp, Dept Obstet & Gynecol China Med Univ Hosp, Div Cardiol Yuan Rung Hosp, Sect Cardiol Chia Nan Univ Pharm & Sci, Dept Hosp & Hlth Care Adm MeiHo Univ, Dept Nursing Taipei Med Univ, Coll Med, Sch Med, Dept Surg Bharathiar Univ, Dept Biotechnol China Med Univ, Dept Biol Sci & Technol China Med Univ, Sch Chinese Med Asia Univ, Dept Hlth & Nutr Biotechnol
Keywords:	arthritis atherosclerosis cancer inflammation neurological disorders
Date:	2018-09
Issue Date:	2019-12-16 09:35:48 (UTC+8)
Publisher:	WILEY
Abstract:	Increasing reports on epidemiological, diagnostic, and clinical studies suggest that dysfunction of the inflammatory reaction results in chronic illnesses such as cancer, arthritis, arteriosclerosis, neurological disorders, liver diseases, and renal disorders. Chronic inflammation might progress if injurious agent persists; however, more typically than not, the response is chronic from the start. Distinct to most changes in acute inflammation, chronic inflammation is characterized by the infiltration of damaged tissue by mononuclear cells like macrophages, lymphocytes, and plasma cells, in addition to tissue destruction and attempts to repair. Phagocytes are the key players in the chronic inflammatory response. However, the important drawback is the activation of pathological phagocytes, which might result from continued tissue damage and lead to harmful diseases. The longer the inflammation persists, the greater the chance for the establishment of human diseases. The aim of this review was to focus on advances in the understanding of chronic inflammation and to summarize the impact and involvement of inflammatory agents in certain human diseases.
Relation:	International Journal of Urology, v.233, n.9, pp.6458-6471
Appears in Collections:	[Dept. of Hospital and Health (including master's program)] Periodical Articles

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