English  |  正體中文  |  简体中文  |  Items with full text/Total items : 17776/20117 (88%)
Visitors : 11074588      Online Users : 612
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/32248

    標題: Sequential Biotransformation of Antcin K by Bacillus subtilis ATCC 6633
    作者: Chang, Te-Sheng
    Chiang, Chien-Min
    Siao, Yi-Yun
    Wu, Jiumn-Yih
    貢獻者: Natl Univ Tainan, Dept Biol Sci & Technol
    Chia Nan Univ Pharm & Sci, Dept Biotechnol
    Natl Quemoy Univ, Dept Food Sci
    關鍵字: Antrodia cinnamomea
    antcin K
    Bacillus subtilis
    日期: 2018-09
    上傳時間: 2019-11-15 15:46:44 (UTC+8)
    出版者: MDPI
    摘要: The biotransformation of antcin K, a major ergostane triterpenoid from the fruiting bodies of Antrodia cinnamomea, by Bacillus subtilis (B. subtilis) ATCC 6633 was studied. Four metabolites from the biotransformation were isolated with preparative high-performance liquid chromatography and identified as 25S-antcin K 26-O-beta-glucoside, 25R-antcin K 26-O-beta-glucoside, 25S-antcin K 26-O-beta-(6'-O-succinyl)-glucoside, and 25R-antcin K 26-O-beta-(6'-O-succinyl)-glucoside with mass and nuclear magnetic resonance spectral analysis. By using either 25S-antcin K 26-O-beta-glucoside or 25R-antcin K 26-O-beta-glucoside as the biotransformation precursor, it was proven that 25S-antcin K 26-O-beta-(6'-O-succinyl)-glucoside and 25R-antcin K 26-O-beta-(6'-O-succinyl)-glucoside were biotransformed from 25S-antcin K 26-O-beta-glucoside and 25R-antcin K 26-O-beta-glucoside, respectively. To the best of our knowledge, this is the first study on the glycosylation of triterpenoids from A. cinnamomea, and the first time the succinylation of triterpenoid glycosides by microorganisms has been found. In addition, all four antcin K glucoside derivatives are new compounds.
    link: http://dx.doi.org/10.3390/catal8090349
    關聯: Catalysts, v.8, n.9, 349
    Appears in Collections:[生物科技系(所)] 期刊論文

    Files in This Item:

    File Description SizeFormat
    10.3390-catal8090349.pdf3053KbAdobe PDF167View/Open

    All items in CNU IR are protected by copyright, with all rights reserved.

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback