Risk of sexually transmitted infections following depressive disorder A nationwide population-based cohort study A nationwide population-based cohort study

doi:10.1097/MD.0000000000012539

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Title:	Risk of sexually transmitted infections following depressive disorder A nationwide population-based cohort study A nationwide population-based cohort study
Authors:	Huang, Sheng-Yun Hung, Jeng-Hsiu Hu, Li-Yu Huang, Min-Wei Lee, Shyh-Chyang Shen, Cheng-Che
Contributors:	Taichung Vet Gen Hosp, Dept Psychiat Taichung Vet Gen Hosp, Chiayi Branch, Dept Psychiat Taipei Tzu Chi Hosp, Dept Obstet & Gynecol, Buddhist Tzu Chi Med Fdn Tzu Chi Univ, Sch Med Taipei Vet Gen Hosp, Dept Psychiat Natl Yang Ming Univ, Sch Med China Med Univ, Sch Med Chia Nan Univ Pharm & Sci, Dept Informat Management Taichung Vet Gen Hosp, Chiayi Branch, Dept Orthoped Natl Chung Cheng Univ, Ctr Innovat Res Aging Soc
Keywords:	chlamydia depression gonorrhoeae human immunodeficiency virus sexually transmitted infections syphilis warts
Date:	2018-10
Issue Date:	2019-11-15 15:45:59 (UTC+8)
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Abstract:	Depressive disorder is a severe mental disorder associated with functional and cognitive impairment. Numerous papers in the literature investigated associations between sexually transmitted infections (STIs) and psychiatric illnesses. However, the results of these studies are controversial. . We explored the relationship between depressive disorder and the subsequent development of STIs including human immunodeficiency virus (HIV) infection, primary, secondary, and latent syphilis, genital warts, gonorrhea, chlamydial infection, and trichomoniasis. We identified patients who were diagnosed with the depressive disorder in the Taiwan National Health Insurance Research Database. A comparison cohort was constructed of patients without the depressive disorder who were matched according to age and sex. The occurrence of subsequent new-onset STIs was evaluated in both cohorts. The depression cohort consisted of 5959 patients, and the comparison cohort consisted of 23,836 matched control patients without depressive disorder. The incidence of subsequent STIs (hazard ratio [HR] 1.54, 95% confidence interval [CI] 1.34-1.76) was higher among the depressed patients than among the patients in the comparison cohort. Furthermore, female gender compared to male (HR 1.58, 95% CI 1.24-2.01) and young age <40-year-old (HR 1.79, 95% CI 1.38-2.32) are both risk factors for acquisition of STIs in depression patient. For individual STI, the results indicated that the patients with depressive disorder exhibited a markedly higher risk for subsequent STIs including HIV infection, syphilis, genital warts, gonorrhea, chlamydial infection, and trichomoniasis. Depressive disorder might increase the risk of subsequent newly diagnosed STIs including HIV infection, syphilis, genital warts, gonorrhea, chlamydial infection, and trichomoniasis in Taiwan population. Clinicians should pay particular attention to STIs in depression patients. Depression patients, especially those with the history of high-risk sexual behaviors, should be routinely screened for STIs.
???metadata.dc.relation.uri???:	http://dx.doi.org/10.1097/MD.0000000000012539
Relation:	Medicine, v.97, n.43, e12539
Appears in Collections:	[Dept. of Information Management] Periodical Articles

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