Chia Nan University of Pharmacy & Science Institutional Repository:Item 310902800/32166
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    標題: Association between acute methanol poisoning and subsequent mortality: a nationwide study in Taiwan
    作者: Chung, Jui-Yuan
    Ho, Chung-Han
    Chen, Yi-Chen
    Chen, Jiann-Hwa
    Lin, Hung-Jung
    Wang, Jhi-Joung
    Hsu, Chien-Chin
    Huang, Chien-Cheng
    貢獻者: Cathay Gen Hosp, Dept Emergency Med
    Chi Mei Med Ctr, Dept Med Res
    Chia Nan Univ Pharm & Sci, Dept Pharm
    Fu Jen Catholic Univ, Sch Med
    Chi Mei Med Ctr, Dept Emergency Med
    Southern Taiwan Univ Sci & Technol, Dept Biotechnol
    Taipei Med Univ, Dept Emergency Med
    Natl Cheng Kung Univ, Dept Environm & Occupat Hlth, Coll Med[Huang, Chien-Cheng
    Southern Taiwan Univ Sci & Technol, Dept Senior Serv
    Chi Mei Med Ctr, Dept Geriatr & Gerontol
    Chi Mei Med Ctr, Dept Occupat Med
    關鍵字: Methanol
    日期: 2018-08-07
    上傳時間: 2019-11-15 15:43:27 (UTC+8)
    出版者: BMC
    摘要: Background: Methanol poisoning (MP) often causes acute mortality and morbidities; however, the association between MP and subsequent mortality has not been well studied. Methods: We conducted a nationwide population-based cohort study by identifying 621 participants with MP from the Nationwide Poisoning Database and 6210 participants without MP from the Longitudinal Health Insurance Database 2000 by matching the index date at a 1:10 ratio between 1999 and 2012. Comparison of the mortality rate between the two cohorts was performed by following up until 2013. Results: A total of 249 (40%) participants with MP and 154 (2.5%) participants without MP died during the follow-up (p < 0.001). Statistic analysis showed that participants with MP had a higher risk for mortality than did the participants without MP (adjusted hazard ratio [AHR]: 13.48; 95% confidence interval [CI]: 10.76-16.88). The risk of mortality was highest in the first 6 months after MP (AHR: 480.34; 95% CI: 117.55-1%2.75). Hypertension, chronic obstructive pulmonary disease, liver disease, malignancy, drug abuse, and lower monthly income also predicted mortality. Conclusions: MP was associated with increased subsequent mortality. Close follow-up for comorbidity control and socioeconomic assistance are suggested for patients with MP.
    關聯: Bmc Complementary and Alternative Medicine, v.18, 985
    显示于类别:[藥學系(所)] 期刊論文


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