在今日空氣汙染嚴重的環境中，選擇適當的洗髮產品維護個人的清潔衛生已是一重要課題並受大家的重視。然而洗髮的清潔用品，市面上的劑型種類繁多，如:凝膠劑型、粉劑產品、液劑、乳劑產品…等等。這些產品在使用時除了具清潔能力外，對身體必須是溫和且安全沒有刺激的。
因此開發如此優質且為人們需求的洗髮產品是刻不容緩的事情；然而對於清潔能力的評估方式以及配方原料對產品性質的影響方面，能夠參考的資料卻是寥寥無幾相當有限。 因此本研究以探討成份組成對產品物化性的影響並建立產品的清潔力之測定方法為研究目標。實驗以Sodium Laureth Sulfate和Ammonium Lauryl Sulfate作為主要界面活性劑，在配方中以不同的比例之添加，再分別添加四種不同的增稠劑，所得的配方產品做物性評估並利用自行建立的清潔力測定法進行有效性評估，以篩選性質最佳之洗髮精配方產品。 綜合各項物性及有效性評估，和安全性貼布試驗，評估選出最佳配方F5與F17，兩者同時具備了良好的有效性質及安定性，其安定性皆為100%。有效性方面，經由加速老化84天後，F5清除力呈現上升的趨勢，並達到了80%；F17經由加速老化84天後其清除力較穩定，並維持在38%。另外在安全性貼布試驗，F5與F17對受測者們皆無引起任何過敏性的刺激反應。兩者都具有優質的外觀其配方組成分別如下：F5為Sodium Laureth Sulfate 11.2%、Ammoniun Lauryl Sulfate 2.8%、Polyquaternium-7 0.5%、PEG6000DS 1%、NaCl 0.25%、Cocamide MEA 1%、Glycerin 2%、1,3 B.G 3%、Germall-115 0.5%、D.W 77.75%；F17為Sodium Laureth Sulfate 11.2%、Ammoniun Lauryl Sulfate 2.8%、Polyquaternium-7 0.5%、Xanthan gum 0.8%、Glycerin 2%、1,3 B.G 3%、Germall-115 0.5%、D.W 79.2%。 The use of shampoo products play an important role in maintaining personal hygienes due to the enviromental pollution by chemicals. Shampoo cosmetics are many types in commmercially available such as gel, power, liquid…etc. They must be effective and very safe with respective to hair and eye during washing. Such an elegant shampoo is needed for people, however, little attention has been given to their efficacy and safety in patents and reports.
The objectives of the present study were to investigate the influence of different compositions on physicochemical properties to establish a method for determinating their efficacy. To formulate shampoo products, the mixture of Sodium Laureth Sulfate with Ammonium Lauryl Sulfate at varying ratio was selected as surfactants and four different thickeners were incorporated individually. As a result, these formulated shampoo products were characterized by physicochemical method and the skin patch test was performed. In addition, their cleansing ability was evaluated using home-made determining method.The results showed that both F5 and F17 were the desired shampoo products with good storage stability at 45℃ for 84 days(C%=100%) and their cleansing ability is up to 80% and 38% at 45℃ accelerated test, respectively. In skin patch test, they don’t show the two products allergic reaction. In addition, the two elegant shampoo were both esthetic appearance. one (F5) is composed of Sodium Laureth Sulfate 11.2%、Ammoniun Lauryl Sulfate 2.8%、Polyquaternium-7 0.5%、PEG 6000DS 1%、NaCl 0.25%、Cocamide MEA 1%、Glycerin 2%、1,3 B.G 3%、Germall-115 0.5%、D.W 77.75%, and the other(F17) is composed of Sodium Laureth Sulfate 11.2%、Ammoniun Lauryl Sulfate 2.8%、Polyquaternium-7 0.5%、Xanthan gum 0.8%、Glycerin 2%、1,3B.G 3%、Germall-115 0.5%、D.W 79.2%。
