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    Please use this identifier to cite or link to this item: http://ir.cnu.edu.tw/handle/310902800/31796

    標題: Recent upper gastrointestinal panendoscopy increases the risk of pyogenic liver abscess
    作者: Tsai, Ming-Jen
    Lu, Chin-Li
    Huang, Ying C.
    Liu, Chung Hsien
    Huang, Wan-Ting
    Cheng, Kai-Yuan
    Chen, Solomon Chih-Cheng
    貢獻者: Ditmanson Med FdnChia Yi Christian Hosp, Dept Emergency Med
    Chia Nan Univ Pharm & Sci, Dept Sports Management
    Natl Cheng Kung Univ, Dept Publ Hlth, Coll Med
    Kaohsiung Med Univ, Dept Emergency Med, Med Ctr
    Kaohsiung Med Univ, Sch Med
    Ditmanson Med FdnChia Yi Christian Hosp, Dept Med Res
    Heng Chun Christian Hosp, 21 Hengxi Rd, Hengchun Township 946, Pingtung County, Taiwan
    Taipei Med Univ, Coll Med, Sch Med, Dept Pediat
    關鍵字: Appendicitis
    Gastrointestinal endoscopy
    Pyogenic liver abscess
    日期: 2017-04-28
    上傳時間: 2018-11-30 15:57:06 (UTC+8)
    出版者: Baishideng Publishing Group Inc
    摘要: AIM To investigate the association between a recent gastrointestinal (GI) endoscopy and the subsequent risk of pyogenic liver abscess (PLA). METHODS We designed a nested case control study. Using the Taiwan National Health Insurance Research Database, 2135 patients with a first diagnosis of PLA were identified from 1998 to 2011. Another 10675 patients without PLA matched by age and sex were selected as reference controls. We identified and compared the possible risk factors for PLA and GI endoscopies performed before the index date (when PLA was diagnosed) between the two cohorts. Multivariate analysis was conducted to examine the risk of PLA within the 90 d after the GI endoscopies. RESULTS Patients with a history of diabetes [adjusted odds ratio (aOR) = 4.92, 95%CI: 1.78-13.61], end-stage renal disease (aOR = 3.98, 95%CI: 1.45-10.91), biliary tract infection (aOR = 2.68, 95%CI: 2.11-3.40), liver cirrhosis (aOR = 2.19, 95% CI: 1.39-3.46), GI malignancies (aOR = 5.68, 95% CI: 4.23-7.64), appendicitis (aOR = 3.16, 95%CI: 2.27-4.41), diverticulitis (aOR = 1.64, 95%CI: 1.01-2.64), and recent endoscopic retrograde cholangiopancreatography (aOR = 27.04, 95%CI: 11.65-62.72) were significantly associated with an increased risk of PLA. After adjusting for the above risk factors and the frequency of outpatient department visits and abdominal ultrasounds during 90 d before the index date, an upper GI panendoscopy (aOR = 2.75, 95%CI: 2.05-3.69) but not a lower GI endoscopy (aOR = 1.07, 95%CI: 0.62-1.86) was significantly associated with PLA. CONCLUSION An upper GI panendoscopy performed before 90 d may increase the risk of PLA.
    關聯: World Journal of Gastroenterology, v.23, n.16, pp.2948-2956
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