Demographic and clinical characteristics of carbon monoxide poisoning: nationwide data between 1999 and 2012 in Taiwan

doi:10.1186/s13049-017-0416-7

CNU IR > Pharmacy and Science > Dept. of Pharmacy > Periodical Articles > Item 310902800/31777

Please use this identifier to cite or link to this item: https://ir.cnu.edu.tw/handle/310902800/31777

Title:	Demographic and clinical characteristics of carbon monoxide poisoning: nationwide data between 1999 and 2012 in Taiwan
Authors:	Huang, Chien-Cheng Ho, Chung-Han Chen, Yi-Chen Lin, Hung-Jung Hsu, Chien-Chin Wang, Jhi-Joung Su, Shih-Bin Guo, How-Ran
Contributors:	Chi Mei Med Ctr, Dept Emergency Med Natl Cheng Kung Univ, Dept Environm & Occupat Hlth Southern Taiwan Univ Sci & Technol, Bachelor Program Senior Serv Chi Mei Med Ctr, Dept Geriatr & Gerontol Chi Mei Med Ctr, Dept Occupat Med Chi Mei Med Ctr, Dept Med Res Chia Nan Univ Pharm & Sci, Dept Pharm Southern Taiwan Univ Sci & Technol, Dept Biotechnol Taipei Med Univ, Dept Emergency Med Southern Taiwan Univ Sci & Technol, Dept Leisure Recreat & Tourism Management Chi Mei Med Ctr, Dept Med Res Natl Cheng Kung Univ Hosp, Dept Occupat & Environm Med
Keywords:	Carbon monoxide poisoning Descriptive analysis Nationwide
Date:	2017-07-14
Issue Date:	2018-11-30 15:56:21 (UTC+8)
Publisher:	Biomed Central Ltd
Abstract:	Background: Carbon monoxide poisoning (COP) is not uncommon, but nationwide epidemiological data are limited. We conducted a study in Taiwan to fill the data gaps. Methods: We used a nationwide poisoning database to study all COP patients in Taiwan diagnosed between 1999 and 2012. We conducted descriptive analyses and compared the differences between the two sexes. In addition, we assessed the trends in suicide and mortality rates from 1999 to 2012. Results: We identified 25,912 COP patients with an almost equal female and male distribution (50.6% vs. 49.4%). The mean age was 36.0 years, and most of the patients were between 20 and 50 years old. The highest incidence rate in the year occurred during winter. While female patients were more likely to have mental disorders (35.9% vs. 28.1%, p < 0.001), male patients were more likely to be resulted from suicide attempts (22.9% vs. 17.7%, p < 0.001). In both sexes, the suicidal rate increased from 1999, reached the peak in 2007, and then decreased gradually. Hyperbaric oxygen therapy was performed in 24.2% of the patients. Neurological sequelae developed in 9.1% of the patients, and chronic respiratory failure and requirement of long-term care were observed in 5.0% and 0.1% of the patients. The 1-month and 3-month mortality rates were 1.6% and 5.0%. The 3-month mortality rate did not show significant change between 1999 and 2012. Discussion: This study showed a whole picture of COP in Taiwan, which could add to the important knowledge of this disastrous problem in public health. Conclusion: Some important findings, including higher percentages of mental disorders in female patients and suicide attempt in male patients, seasonal changes, and trends in mortality and morbidity (suicide) rates, may help developing strategies for prevention and treatment of COP.
Relation:	Scandinavian Journal of Trauma Resuscitation & Emergency Medicine, v.25, pp.70
Appears in Collections:	[Dept. of Pharmacy] Periodical Articles

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