A new flavonol from the kino of Eucalyptus citriodora

Chia Nan University of Pharmacy & Science Institutional Repository > 藥理學院 > 食藥產業暨檢測科技系(含五專) > 期刊論文 > Item 310902800/31734

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標題:	A new flavonol from the kino of Eucalyptus citriodora
作者:	Lee, Shwu-Woan Hung, Wei-Jing Chen, Zong-Tsi
貢獻者:	Chia Nan Univ Pharm & Sci, Dept Med Chem Chia Nan Univ Pharm & Sci, Dept Cosmet Sci Chia Nan Univ Pharm & Sci, Inst Cosmet Sci
關鍵字:	Eucalyptus citriodora kino lipoxygenase flavonoids
日期:	2017
上傳時間:	2018-11-30 15:54:41 (UTC+8)
出版者:	Taylor & Francis Ltd
摘要:	A new flavonol, 6-[1-(p-hydroxyphenyl)ethyl]rhamnocitrin (3) together with two known compounds, kaempferol (4) and 7-O-methyl aromadendrin (5) were isolated from the kino of Eucalyptus citriodora and their structures were elucidated on the basis of spectroscopic methods including 2D NMR spectra. Rhamnocitrin (1), 6-[1-(p-hydroxyphenyl)ethyl]-7-O-methyl aromadendrin (2), previously isolated from this plant and compounds 3-5 were tested for inhibitory activity against 15-lipoxygenase. All compounds exhibited moderate to strong inhibitory activities, of which compounds 2, 3 and 5 showed stronger inhibitory activity (IC50 19.7 +/- 0.5, 29.3 +/- 0.9 and 31.4 +/- 1.0M, respectively) than the positive control quercetin (IC50 37.5 +/- 0.8M).
關聯:	Natural Product Research, v.31, n.1, pp.37-42
显示于类别:	[化妝品應用與管理系(所)] 期刊論文 [食藥產業暨檢測科技系(含五專)] 期刊論文

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